SUPRAVA TZ 1.25GM INJECTION

SUPRAVA TZ 1.25GM INJECTION


BIOCON
1 VIAL (1 )
*This medicine require prescription*
Salts Substitutes
Salts
Uses

Gonorrhea Pelvic inflammatory disease Middle ear infection Meningitis (inflammation of the covering of the brain) Infections of the lungs, ears, skin, urinary tract, blood, bones and joints Typhoid


Mechanism of Action

It kills the bacteria by interrupting the bacterial cell wall (outer coating of bacteria) formation due to which the bacterial cell wall is weakened and ruptured, thereby killing the bacteria


Dosage
Middle ear infection: Children - IM A single dose of 50 mg/kg (max, 1 gram) is recommended Meningitis in children: Children - IV: Recommended initial dose is 100 mg/kg (max, 4 gram), followed by 100 mg/kg/day (max, 4 gram/day) for 7 to 14 days Skin or Skin Structure Infections: Children - IV/IM: Recommended daily dosage is 50 to 75 mg/kg once a day or in equally divided doses twice daily (max, 2 gram/day) Surgical Prophylaxis: Adults - IV: 1 gram as a single dose 30 min to 2 hours before surgery Uncomplicated Gonococcal Infections: Adults - IM: 250 mg as single dose Miscellaneous Infections: Adults - IV: Usual adult daily dosage is 1 to 2 g once a day or in equally divided doses twice daily, depending on the type and severity of infection (max, 4 gram/day)

Side Effects
Dizziness, Headache Diarrhea, nausea and vomiting High concentration of eosinophils, platelet counts in the blood, decrease in white blood cells, low prothrombin levels, bleeding Increase in liver enzyme, elevated BUN (Blood urea, nitrogen) Indurations/tightness/warmth Vaginal inflammation Fatal ceftriaxone-calcium precipitates in lung and kidneys of neonates

Warnings/Precautions
Caution should be exercised in patients with history of penicillin allergy; severe renal impairment; pregnancy and lactation; problem with digestive system, especially colitis (inflammation of the large intestine), malnutrition (you do not eat or cannot digest the nutrients needed for good health), super infection Be sure for the full course of treatment. If you do not, the medicine may not clear up your infection completely
Uses

Tazobactam is an antibiotic used in combination with another antibiotic calledpiperacillin to treat many infectionscaused by bacteria, such as urinary tract infections, bone and jointinfections, severe vaginal infections, stomach infections, skin infections, andpneumonia. It is also used to treat complicatedintra-abdominal infections including inflammation of the membrane which linesthe inside of the abdomen and the entire internal organs It is also used to treatdecrease in white blood cells (neutropenia) with fever due to bacterialinfection.


Mechanism of Action
Tazobactam belongs to group of

Dosage
Always follow the instructions of doctor regarding the dosage and durationTreatment of bacterial infection(doses for injection use):Adults and adolescents (age 12 years or older): 0.5 g tazobactam + 4 g piperacillin given every 6-8 hoursChildren (age 2 to 12 years): 100 mg/12.5 mg per kg of body weight of piperacillin / tazobactam given every 8 hours

Side Effects
Diarrhea, nausea, vomiting, and skin rashSecondary infection by a fungus, abnormal blood counts, severe allergic (hypersensitivity)reaction, headache, unable to sleep (insomnia), low blood pressure, pain and swelling due to inflammation of a vein, inflammation of a vein caused by a blood clot, constipation, indigestion (dyspepsia), jaundice, inflammation of mouth and lips, , increased liver enzymes, increased blood creatinine, pale red, raised, itchy skin rash, injection site reactions, hypersensitivity reactions

Warnings/Precautions
It is given as an infusion (a drip for 30 minutes) into a vein.Tell the doctor if you have to provide a blood or urine sample for any test because tazobactam and piperacillin may cause false positive results.Do not start or continue the tazobactam/piperacillin and consult your doctor:If you are suffering from diarrhea before, or during the treatment with the drugIf you have kidney or liver problems, low levels of potassium in the blood, or are receiving hemodialysisIf you develop new or worsening infection, or fits (convulsions) during the treatmentIf you are on a controlled-sodium dietIf you are pregnant or planning to become pregnant or breastfeeding
Substitutes
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