SUTENT 25MG CAPSULE

Sunitinib is used in the treatment of gastrointestinal stromal tumor (GIST, tumor that occurs in thegastrointestinal tract, most commonly in the stomach or small intestine) that cannot be treated by imatinib; metastatic renal cell carcinoma (MRCC, cancer that has spread beyond its site of origin in the kidney, to other organs in the body) and pancreatic neuroendocrine tumor (PNET, tumor of the hormone producing cells of the pancreas)

• Sunitinib inhibits the proteins that signal growth and spread of cancer cells
• This result in stopping or slowing the spread of cancerous cells and helps shrink the tumors

• For gastrointestinal stromal tumor renal cell carcinoma- Adult- PO- The recommended dose is one 50 mg once daily, on a schedule of 4 weeks on treatment followed by 2 weeks off
• For pancreatic neuroendocrine tumors -The recommended dose is 37.5 mg taken orally once daily continuously without a scheduled off-treatment period

• Loss or decrease of appetite
• Nasal congestion
• Abdominal pain or swelling
• Increased blood pressure
• Shortness of breath or coughing up blood or bloody sputum
• Pricking sensation
• Difficulty in falling asleep or maintain sleep
• Decreased capacity of heart to function
• Bleeding nose
• Change in color of hair
• Tingling
• Hot flushes/flushing
• Yellow discoloration of skin

• Please consult your doctor if you have or are going to undergo a surgery, including dental surgery
• Sunitinib maycause dizziness and unusual tiredness. Do not drive or operate machinery or engage in activities requiring mental alertness and coordination, until you feel fine
• Sunitinib cancause your skin to turn yellow and your hair to lighten and lose color. This is normal and not a cause for concern
• Your blood pressure should be checked regularly while you are taking sunitinib as it may cause high blood pressure