SAFEDOL 100MG CAPSULE

• Used in the treatment of painful conditions of joints, lower back pain, sprains or bone fractures
• Inflammation of joints (frozen shoulder, gout)
• Pain and swelling following skeletal muscle
• Dental and other minor surgeries
• It is also used in treatment of migraine

It works by blocking the production of a certain chemical substance in the body that causes pain, fever, and inflammation

• The recommended dosage is 100-200 mgday in divided doses
• Topical- Apply the gel (4 g) to the affected area, 4 times daily

• Dryness, redness, induration, vesicles, itching, dilatation of blood vessels, pimples and hives
• Abdominal pain, accidental injury, allergic reaction, weakness, back pain, body odor, chest pain, fluid retention, face swelling, unpleasant odors, headache, lack of drug effect, neck rigidity, pain
• Palpitation, heart disorder
• Diarrhea, dry mouth, indigestion, stomach flu, decreased appetite, mouth ulcer, nausea, rectal bleeding
• Increased creatinine levels
• Leg cramps, muscle pain
• Depression, dizziness, drowsiness, lethargy, tingling

• Caution should be exercised in patients with history of heart, kidney or liver disease, diabetes, stomach or bowel problems, high blood pressure, blood disorders, bone marrow problems, bleeding problems, blood vessel disease, dehydration, alcoholism, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding
• It may cause dizziness, do not drive a car or operate machinery while taking this medication
• For external use only; avoid contact with eyes, nose, or mouth. It may cause harm if it is swallowed
• Monitor kidney and liver function, blood electrolyte levels, complete blood cell counts, and blood pressure regularly while taking this medication

• Gastric acidity
• gastro-intestinal reflux disease (heart burn)
• stomach
• intestinal ulcers
• diseases associated with excessive acid production (Zollinger Ellison Syndrome)

• Rabeprazole belongs to class of medications called proton pump inhibitors
• It blocks the activity of the proton pumps in the stomach wall that produce acid, thereby reducing the amount of acid produced in the stomach

• Gastro-oesophageal reflux disease; erosive oesophagitis -20 mg once daily in the morning for 4-8 weeks. Maintenance: 10-20 mg once daily
• For non-erosive oesophagitis -10 mg once daily for 4 week, upon symptom resolution, may continue with 10 mg once daily when needed
• Healing of Duodenal Ulcers -20 mg/day after the morning meal for 4 weeks; additional therapy may be required for some patients
• Zollinger-Ellison -60 mg once daily. Adjust according to patient’s needs

• Increased risk of infections
• Abdominal pain
• Constipation
• Chills or sore throat
• Belching
• Flatulence

• Caution should be exercised in patients with history of bleeding ulcer, such as black, tarry stools or vomit that looks like coffee grounds, or if you experience throat pain, chest pain, severe stomach pain, or trouble swallowing contact your doctor immediately
• May increase the risk of GI infections due to acid suppressive effects, liver damage, gastric tumor