Salts
Uses
Mechanism of Action
Dosage
Side Effects
Warnings/Precautions
Fenofibrateis used to treat high cholesterol and high triglyceride levels
Mechanism of Action
Fenofibrate belongs to a class of drugs called as fibrates or fibric acid derivatives. It works by increasing the action of enzyme lipoprotein lipase which decreases the level of fats (triglycerides) in the blood
Dosage
Standard micronised formulation: Initially, 67 mg tid or 200 mg once daily, may reduce to 67 mg bid or increase to 67 mg 4 times daily or 267 mg once daily according to response Non-micronised formulation: Initially, 200-300 mg daily in divided doses. Usual range: 200-400 mg daily Formulation withimproved bioavailability: 40-160 mg once daily may be used
Side Effects
Increased creatinine kinase concentrations abdominal pain back pain asthenia diarrhoea nausea constipation rhinitis flu syndrome muscle pain urticaria mild to moderate decreases in hemoglobin cholecystitis pancreatitis rhabdomyolysis
Warnings/Precautions
If you also take medicines such as cholestyramine or colestipol; make sure to take them at least 1 hour after or 4 hours before taking fenofibrate Consult your doctor, if you have diseases such as diabetes, hyperthyroidism, kidney or liver ailments Do not take fenofibrate, if you are allergic to it or to any other ingredient in the medicine (lactose) Do not take finofibrate, if you are sensitive to sunlight Do not take the medicine, if you are suffering from severe liver, kidney or pancreatic ailments (gall bladder disease, biliary cirrhosis, pancreatitis); if you have muscular disorders, large amount of protein in urine, water retention in the body (nephrotic syndrome), decreased albumin in the blood (hypoalbuminaemia) or poorly controlled diabetes mellitus Do not take the medicine if you are pregnant or breast-feeding
Uses
Mechanism of Action
Dosage
Side Effects
Warnings/Precautions
High cholesterol (hypercholesterolemia) high lipid levels (hyperlipidemia) lower the risk of stroke heart attack, or other heart complications in people with type 2 diabetes disease of coronary artery of heart (coronary heart disease)
Mechanism of Action
- Rosuvastatin belongs to a group of medications called statins (lipid-lowering agents) or HMG CoA reductase inhibitors
- It acts by blocking the enzyme HMG CoA reductase and formation of cholesterol, thus, lowering the blood lipid levels
Dosage
Hyperlipidaemias; Prophylaxis of cardiovascular events in high-risk patients - Adult:Initially, 5 or 10 mg once daily, may increase dose at 4-weekly intervals to 20 mg daily if necessary. Max: 40 mg once daily Child:Heterozygous familial hypercholesterolaemia:≥10 yrInitially, 5 mg once daily, may be adjusted at intervals of at least 4 week. Max: 20 mg once daily
Side Effects
Difficulty in falling asleep Memory loss Abdominal pain Aching joints/joint pains Constipation Stomach pain Dizziness Confusion Weakness
Warnings/Precautions
Do not take antacids for atleast 2 hours before and after taking this drug. Consult your doctor if you develop sudden muscle pain, fever or weakness. Consult your doctor if you notice dark urine or yellowing of eyes or skin. Do not take rosuvastatin if you are allergic (hypersensitive) to rosuvastatin or any of the other ingredients of rosuvastatin. Do not take this drug if you are pregnant or breast-feeding. If you become pregnant while taking rosuvastatin stop taking it immediately and tell your doctor