UsesFits (seizures) pain caused by damage to the nerves generalized anxiety disorders in adults
Mechanism of Action- Pregabalin belongs to group of medications called antiepileptics
- It acts by modifying the release of certain substances released by the nerves in the brain (neurotransmitters) to restrict the transfer of pain signals between nerves, thereby reducing pain caused by damage to the nerves, as well as symptoms of fits (seizures)
DosagePostherpetic neuralgia-Initial-150 mg/day in divided doses. Usual: 150-300 mg/day in divided doses. Max: 600 mg/day in divided doses Adjunct in partial seizures -150-600 mg/day in divided doses. Max: 600 mg/day Fibromyalgia -Initial- 150 mg/day, up to 300 mg/day after 1 week if needed and then 450 mg/day if still needed Anxiety -Initial-150 mg/day. Increase slowly if needed. Max: 600 mg/day
Side EffectsChange in mood Anxiety Difficulty in concentrating Constipation Loss of balance Difficulty in remembering Lack of coordination or jerky movements Muscle twitching Uncontrollable shaking of a body part Speech problems Confusion Bloating and gas
Warnings/PrecautionsDiscontinue treatment if patients develop severe allergic reaction Withdraw treatment gradually over at least 1 week May cause peripheral edema Regular vision check is recommended May decrease platelet count and prolong PR interval Mental health may change in unexpected ways and you may become suicidal (thinking about harming or killing yourself or planning or trying to do so) while you are taking this medication for the treatment of epilepsy