UsesUsed to prevent blood clots (thrombi) forming in hardened blood vessels (arteries)
Mechanism of Action- It’s a “blood thinner”
- It works by blocking certain blood cells called platelets and prevents them from forming harmful blood clots. This "anti-platelet" effect helps keep blood flowing smoothly in your body
DosageOral- Prophylaxis of blood clot events- 75 mg once daily Acute coronary syndrome For ST-elevation myocardial infarction: with aspirin: 75 mg once daily For unstable angina, non-ST-elevation myocardial infarction: Initial: 300 mg loading dose, followed by 75 mg once daily (with aspirin 75-325 mg once daily)
Side EffectsSwelling, high blood pressure, inflammation of blood vessels Headache, dizziness, depression, confusion Rash, itching, severe allergic reactions (severe rash, itching, swelling, severe dizziness, trouble breathing) Stevens-Johnson syndrome, toxic epidermal necrolysis Bleeding in retina, conjunctiva Abdominal pain, diarrhea, stomach upset, nausea, inflammation of colon (including ulcerative or lymphocytic), inflammation of pancreas, mouth ulcer, taste disorders Urinary tract infection, kidney disease, increased creatinine levels Bruising, nose bleeds, anemia, bleeding (including intracranial, GI, and retroperitoneal hemorrhage), and decrease in platelets Abnormality in liver enzymes, inflammation of liver Increase in cholesterol Muscle pain, back pain, muscle weakness Upper respiratory tract infection, difficulty in breathing, inflammation of bronchus, stuffy nose, coughing Accidental injury, chest pain, influenza-like symptoms, fatigue, fainting, hypersensitivity reactions, serum sickness, bleeding of wounds
Warnings/PrecautionsCaution needed for patients at risk of increased bleeding from trauma, surgery, or other pathological conditions; ulcer; liver and kidney impairment; history of bleeding or haemostatic disorders, pregnancy Avoid injury or bruising while taking this medication It may cause dizziness, avoid driving a car or operating machinery, or other unsafe tasks