Salts
Uses
Mechanism of Action
Dosage
Side Effects
Warnings/Precautions
Used to treat respiratory tract infection like lung infection (pneumonia) Urinary tract infections such as kidney infection (pyelonephritis) Skin and soft tissue infections Intra-abdominal infections Fever associated with low white blood cells called neutrophils (febrile neutropenia)
Mechanism of Action
It actsby killingthe bacteria by interrupting the bacterial cell wall (outer coating of bacteria) formation due to whichthe bacterial cell wall is weakened and ruptured, thereby killing the bacteria
Dosage
Intravenous- UTI- The recommended dose is 0.5-1 g 12 hourly for 7-10 days Empirical therapy for febrile neutropenia- 2 g 8 hourly for 7 days or until resolution of neutropenia
Side Effects
Changes in thinking or behavior Difficulty breathing Sore mouth or throat Vomiting Patches Confusion Unusual bleeding after injury Stomach pain, Diarrhea Swelling at the injection site Itchy skin rash
Warnings/Precautions
Caution should be exercised in patients with history of penicillin or cephalosporin allergy, gastro intestinal disease, especially colitis; lactation, pregnancy, seizures It may decrease prothrombin activity; monitor prothrombin time in patients with poor nutritional state, kidney or liver impairment and those on prolonged treatment Prolonged treatment may result in overgrowth of non-susceptible organisms, resulting in superinfection Consider the possibility of Clostridium difficile associated diarrhea in patients who present with diarrhea after treatment Patient may develop with increased risk of neurotoxicity
Substitutes
- MAPIME 250MG INJECTION
62.07
MAPRA LABORATORIES - MAXICEF 250MG INJECTION
67.70
ARISTO PHARMA