UsesIt is used to treat many kinds of bacterial infections
Mechanism of ActionAmikacin belongs to group of medicines called aminoglycosides. It works by interrupting bacterial protein synthesis, produces non-functional peptides, and inhibits the bacterial growth
DosageThe recommended dose is 15mg/kg/day in 1-3 doses urinary tract infection 250mg twice a day.
Side EffectsMuscle weakness (due to blocking of signals from the nerves to the muscles) Hearing loss and loss of balance Reduced urine volume, protein in urine, increased serum creatinine, urinary casts, red and white blood cells in urine and high level of nitrogen waste in blood (azotemia) Decreased serum magnesium
Warnings/PrecautionsDiscontinue, if signs of ototoxicity, neurotoxicity or hypersensitivity occurs Monitor renal function before and during treatment Do not drive because you may feel sleepy or dizzy while being treated with amikacin