Clomifene is used to treat infertility in women caused by failure or improper release of eggs from ovary (ovulation).It is also used to treat infertility in males due to decreased production of sperms (oligozoospermia). Mechanism of Action
Clomifene belongs to a class of medicines known as Dosage
Always follow the instructions of doctor regarding the dosage and duration.Anovulatory infertility in females:Adults: 50 mg daily for 5 days, starting within 5 days of onset of menstruation, (preferably on the second day) or at any time if cycles have stopped; a second course of 100 mg daily for 5 days may be given in the absence of ovulation.Oligozoospermia in males: 25 mg daily given for 24 days in a month with 6 days rest for upto 6 months. Side Effects
Nausea, vomiting, abdominal distention, bloating, headache, abnormally heavy bleeding at menstruation, intra-menstrual bleeding (spotting), multiple cysts in ovaries, vision disturbances, breast discomfort, flushing, endometriosis, pancreatitis (inflammation of pancreas), skin allergies, cataract and changes in liver function test values. Warnings/Precautions
Do not take clomifene tablet if you are allergic to clomifene or to any other content in the medicine.Do not take clomifene if you have liver disease; ovarian cyst; any type of cancer; ovarian cyst; unusual or unexplained menstrual bleeding.Inform your doctor before taking the medicine if you are having an early menopause or if you told you are infertile; or menses have ceased due to pregnancy, underweight, or other reasons.Do not take clomifene if you have had fits or seizures in the past; polycystic ovaries or swelling in the ovaries; or hypertriglyceridemia (increased level of fats in the blood).Avoid using clomifene if you are pregnant or breast-feeding a baby.Do not take these tablets for more than five days at a time.Do not drive or operate heavy machinery if you experience visual disturbances after taking this medicine.This medicine should not be taken by children, adolescents, or by women who have gone through menopause.