It is important in electrolyte and fluid balance, osmotic pressure control and water distribution as it restores sodium ions. It is used as a source of electrolytes and water for hydration, treatment of metabolic acidosis, priming solution in haemodialysis and treatment of hyperosmolar diabetes
It is also used as diluents for infusion of compatible drug additives.
OralChronic salt-losing conditions
Adult:As modified-release preparation: 2.4-4.8 g (40-80 mmol sodium) daily accompanied by suitable fluid intake. Up to 12 g daily may be necessary in severe cases
OralProphylaxis of muscle cramps during routine haemodialysis
Adult:As modified-release preparation: 6-10 g every dialysis session
Adult:Used as mouthwash
Adult:0.9% used as nasal drops or spray.
Child:0.9% used as nasal drops
IntravenousReplacement of fluid and electrolytes
Adult:As 0.9%, 3% or 5% solution: Dosage depends on age, wt, clinical condition and laboratory determinations of the patient. Dose to be administered via a large vein, with care taken to prevent infiltration
Adult:As 0.9% solution: Dosage depends on age, wt, clinical condition and laboratory determinations of the patient. Dose to be administered via a large vein, with care taken to prevent infiltration
Irrigation of the bladder, eye, general skin and wound cleansing