Salts
Uses
Mechanism of Action
Dosage
Side Effects
Warnings/Precautions
Upper and lower respiratory and urinary tract infections Skin, soft tissue, bone and joint infections Septicemia, meningitis, peritonitis, cholecystitis, cholangitis, pelvic inflammatory disease, endometritis Gonorrheaand other abdominal and genital tract infections
Mechanism of Action
It kills the bacteria by interrupting the bacterial cell wall (outer coating of bacteria) formation due to whichthe bacterial cell wall is weakened and ruptures, thereby killing the bacteria
Dosage
Adult: IV/IM- The recommended dose is 2-4 g/day in 2 divided doses, up to 12 g/day for severe infections
Side Effects
Allergic reactions, reversible neutropenia Transient rise in SGOT-SGPT and alkaline phosphatase, eosinophilia, positive direct coombs test, anemia and reduced hematocrite
Warnings/Precautions
Caution should be exercised in patients with history of penicillin allergy, kidney or liver impairment, cystic fibrosis, during pregnancy and breastfeeding Tell your doctor if you are taking cefoperazone and undergoing any blood or urine test, as it may affect the result