PARKIN PLUS 5MG/2MG TABLET

PARKIN PLUS 5MG/2MG TABLET


MICRO LABS
1 STRIP (10 TABLET(S))
*This medicine require prescription*
Salts Substitutes
Salts
Uses

Trifluoperazine is used for the short-term treatment of anxiety or depression and also for the treatment of nausea and vomiting Trifluoperazine may also be used to prevent relapse of schizophrenia (psychiatric disorder with symptoms of emotional instability, detachment from reality, often with delusions and hallucinations, and withdrawal into the self)


Mechanism of Action
  • Trifluoperazine belongs to a category of drugs called as phenothiazine tranquilizers
  • It works by decreasing the activity of neurotransmitter dopamine that causes excitation of brain cells and helps in reducing symptoms of anxiety, depression and schizophrenia

Dosage
Schizophrenia- PO: Usual starting dosage is 2 mg to 5 mg two times per day Non-psychotic Anxiety - Usual dosage is 1 or 2 mg twice daily

Side Effects
Restlessness Blurred vision Muscle weakness and faintness on standing up Drowsiness Insomnia Dry mouth Loss of appetite Water retention causing swelling or confusion Eye problems

Warnings/Precautions
Do not drive vehicle or operate heavy machinery while taking this drug as it may make you feel dizzy Do not consume alcohol while taking trifluoperazine as it may worsen the side effects Consult your doctor before taking trifluoperazine if you are pregnant, planning to become pregnant or breastfeeding
Uses

Trihexyphenidyl is used to treat symptoms of Parkinson’s disease (a type of nerve disease that causes movement disorder characterized by slowness of movements, muscle stiffness, uncontrolled shaking and poor balance and co-ordination) and drug-induced extra pyramidal symptoms (movement disorders similar to symptoms of Parkinson’s disease) except tardive dyskinesia (involuntary movement of face and jaw). It is often given along with levodopa (anti-Parkinson drug)


Mechanism of Action

Trihexyphenidyl is an anticholinergic agent, which works by blocking the action of a chemical called acetylcholine on the nerves which results in relaxing of smooth muscles; thereby, reducing the rigidity of muscle spasm (sudden involuntary contraction of a muscle or group of muscles), tremor (uncontrolled shaking) and excessive salivation associated with Parkinson’s disease


Dosage
Adult- PO- Initial: The recommended dose is 1 mg/day in 3-4 divided doses, increased gradually up to 6-10 mg/day according to response

Side Effects
Anxiety Tachycardia Restlessness Blurring of vision Hallucination Impaired memory Euphoria Difficulty urinating and rash Dryness of mouth

Warnings/Precautions
Trihexyphenidyl is not recommended for use in patients with tardive dyskinesia (involuntary movement of face and jaw) and in children under 18 years of age Trihexyphenidyl is not recommended as prophylaxis (preventive treatment) for drug-induced parkinsonism. Avoid abrupt discontinuation of treatment as it can result in worsening of symptoms of Parkinson’s disease or emergence of life-threatening complications (neuroleptic malignant syndrome) Take precautions while driving or operating machinery as trihexyphenidyl can impair mental and physical abilities Use trihexyphenidyl with caution in hot weather as it can increase susceptibility to heat stroke (symptoms: very high fever, inability to bear heat, nausea, vomiting etc.) Please consult your doctor if you are pregnant or planning to become pregnant or are breastfeeding
Substitutes
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