UsesUsed to treat fungal infections of the skin, fungal infection of the foot and hand It is also used for the prevention and treatment of fungal infection of the scalp including dandruff and yeast infections of the skin
Mechanism of ActionKetoconazole acts mainly by preventing the growth of fungi. It prevents yeasts and fungi from reproducing and from making their protective outer cell wall
DosageAdult- The oral dose range is 200-400 mg daily Topical formulations are administered over affected areas once or twice daily
Side EffectsHeadache, dizziness, drowsiness, fever, chills Sensitivity to light, diarrhea, nausea, vomiting Breast enlargement in male, impotence Decrease in platelet counts and white blood cells Anemia, projection of skull bone,hair loss
Warnings/PrecautionsCaution should be exercised in patients with history of liver disease, alcoholism, blood problems (eg, prophyria), any allergy, who are taking other medications, during pregnancy and breastfeeding It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication It may affect blood sugar level; monitor sugar level regularly