KEFBACTUM 2GM INJECTION

KEFBACTUM 2GM INJECTION


ELDER PHARMACEUTICALS
1 VIAL (10 ML)
*This medicine require prescription*
Salts Substitutes
Salts
Uses

Upper and lower respiratory and urinary tract infections Skin, soft tissue, bone and joint infections Septicemia, meningitis, peritonitis, cholecystitis, cholangitis, pelvic inflammatory disease, endometritis Gonorrheaand other abdominal and genital tract infections


Mechanism of Action

It kills the bacteria by interrupting the bacterial cell wall (outer coating of bacteria) formation due to whichthe bacterial cell wall is weakened and ruptures, thereby killing the bacteria


Dosage
Adult: IV/IM- The recommended dose is 2-4 g/day in 2 divided doses, up to 12 g/day for severe infections

Side Effects
Allergic reactions, reversible neutropenia Transient rise in SGOT-SGPT and alkaline phosphatase, eosinophilia, positive direct coombs test, anemia and reduced hematocrite

Warnings/Precautions
Caution should be exercised in patients with history of penicillin allergy, kidney or liver impairment, cystic fibrosis, during pregnancy and breastfeeding Tell your doctor if you are taking cefoperazone and undergoing any blood or urine test, as it may affect the result
Uses

Sulbactam is used in combination with other antibiotics for treating certain bacterial infections It is used to treat intraabdominal, gynecological, skin or soft tissue, and surgal infections, especially those developed in the hospital


Mechanism of Action
  • Sulbactam belongs to group of medicines called betalactamase Inhibitor with very weak action against bacteria
  • Beta-lactamase inhibitors are available only in fixed combinations with specific penicillins (beta-lactam antibiotics) such as amoxicillin, ampicillin, piperacillin, and ticarcillin
  • It works by preventing destruction of beta-lactam antibiotics from chemicals released from bacteria and extends their spectrum of activity

Dosage
IntravenousGynaecological infections; Intra-abdominal infections; Skin and skin structure infections Adult:1.5 g (1 g ampicillin/0.5 g sulbactam) -3 g (2 g ampicillin/1 g sulbactam) every 6 hr. Max: 4 g sulbactam/day Child:≥1 yr: 300 mg/kg daily (200 mg ampicillin/100 mg sulbactam), given via IV infusion in equally divided doses every 6 hr. ≥40 kg: 1.5 g (1 g ampicillin/0.5 g sulbactam) -3 g (2 g ampicillin/1 g sulbactam) IM/IV every 6 hr. Max treatment duration: 14 days IntravenousAcute pelvic inflammatory disease Adult:3 g (2 g ampicillin/1 g sulbactam) every 6 hr with doxycycline. Discontinue IV therapy 24 hr after clinical improvement; continue with oral doxycycline (100 mg bid) for 14 days to complete treatment

Side Effects
Inflammation of a vein caused by a blood clot Rash Diarrhea Pain at site of injection

Warnings/Precautions
Please consult yourdoctor if you have diabetes and regularly check your urine for sugar level; ampicillin and sulbactam may cause false positive results Before start or continue the sulbactam and consult your doctor If you have asthma, runny nose due to allergy (hay fever), or kidney or gastrointestinal disease especially inflammation of large intestine (colitis), If you are pregnant or planning to become pregnant or breastfeeding or become pregnant while taking ampicillin and sulbactam
Substitutes
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