UsesGefitinib is used to treat adults with non-small cell lung cancer (locally advanced or distance spread [metastasis])
Mechanism of ActionGefitinib blocks a protein called ‘epidermal growth factor receptor’ (EGFR) which is involved in the growth and spread of cancer cells
DosageAdult- The recommended daily dose is one 250 mg
Side EffectsBleeding Red and sore eyelids Nausea Inflammation of the liver Dehydration Vomiting Increase of bilirubin and liver enzymes Burning sensations during urination lung disease Increase of creatinine levels Loss of appetite Inflammation of the pancreas Fever Hair loss Skin reactions such as an acne-like rash
Warnings/PrecautionsDo not take antacids (to reduce the acid level of your stomach) 2 hours before or 1 hour after taking gefitinib Take the tablet at about the same time each day Do not give gefitinib to children Do not take gefitinib, if you are allergic to gefitinib or similar medicines or to any of the other ingredients Avoid using gefitinib, if you are pregnant or are breast-feeding Avoid becoming pregnant during treatment with gefitinib because it could harm your baby If you are taking a medicine containing warfarin as an active substance, your doctor may need to do blood tests more often You may feel weak while taking this medicine, be careful while driving or using tools or machines