GEMBIN 200MG INJECTION

• Gemcitabine is used in combination with other drugs for the treatment of local or advanced cancers like non-small cell lung cancer, epithelial ovarian cancer, bladder cancer, adenocarcinoma of the pancreas
• It is also used for treating recurrent breast cancer that cannot be treated with surgery

• Gemcitabine belongs to a class of medication called anti-metabolites
• It is cytotoxic in nature
• They kill rapidly dividing cells (e.g. cancer cells) thus slowing down the spread of cancer in the body

• Advanced non-small cell lung cancer- 1 g/m2on days 1, 8 and 15 of each 28-day cycle
• Pancreatic cancer- 1 g/m2once weekly for up to 7 weeks followed by 1 week rest. Continue thereafter with once weekly infusions for 3 consecutive weeks out of 4
• Bladder cancer- 1 g/m2on days 1, 8 and 15 of each 28-day cycle. To be given before cisplatin
• Breast cancer- 1.25 g/m2on days 1 and 8 of each 21-day cycle
• Ovarian carcinoma- 1 g/m2on days 1 and 8 of each 21-day cycle. To be given before carboplatin

• Loss of hair; muscle or back pain
• Unusual tiredness or weakness; flu or fever
• Eating disorders
• Inflammation or sores of the inside area of mouth or digestive tract
• Nausea
• Cough or runny nose
• Sweating or itching
• Low production of blood cells in bone marrow
• Liver problems
• Skin rashes
• Chills
• Vomiting
• Bleeding or protein in urine
• Breathing difficulty
• Constipation
• Diarrhea
• Sleepiness
• Pain in stomach

• Caution should be exercised in patients with history of bone marrow depression, liver, kidney impairment and radiation therapy
• Avoid vaccination while taking this medication
• It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication
• Avoid alcohol consumption while taking this medication
• It may lead to poor blood clot, avoid bruising or injury
• It may affect the menstrual cycle in women and stop sperm production in men