UsesVecuronium is used along with general anesthesia for an easy placement of flexible plastic tube into the airway (tracheal intubation) and also to provide skeletal muscle relaxation during surgery
Mechanism of Action- Vecuronium belongs to a group of medicines called muscle relaxants
- It works by blocking the signalling process between the nerves and muscles, which results in muscle relaxation
DosageAdult: IV- Facilitate endotracheal intubation; Muscle relaxant in general anesthesia- Initial: 80-100 mcg/kg as injection Maintenance: 20-30 mcg/kg, adjust according to response Alternatively, as continuous infusion at 0.8-1.4 mcg/kg/min after initial IV dose of 40-100 mcg/kg
Side EffectsPain near the site of injection Allergic reactions Wheezing Rash/Redness of the skin Swelling Muscle weakness
Warnings/PrecautionsPlease consult your doctor if you are suffering from any of the following medical conditions: liver, biliary tract disease or kidney failure, heart disease with increased circulation time, neuromuscular disease, hypothermia, burns, obesity, electrolyte disturbances, altered blood pH or dehydration Seek medical advice while taking vecuronium as there is an increased risk of inadequate neuromuscular recovery (residual neuromuscular blockade) Before drug administration you may be tested for hypersensitivity as vecuronium is known to cause severe allergic reactions