UsesTreating type 2 diabetes in patients who cannot control blood sugar levels by diet and exercise alone It isusedalong with diet and exercise It may beusedalone or with other antidiabetic medicines
Mechanism of Action- Glimepiride stimulates the insulin release from pancreatic β-cells and reduces glucose output from the liver
- It also increases insulin sensitivity at peripheral target sites
DosageInitial- The recommended starting dose is 1-2 mg once daily, with food Maximum -2mg/day
Side EffectsDizziness Anaemia Hunger pangs Restlessness Vomitting Low blood sugar level symptoms Abnormal blood counts Sluggishness Problems with sleeping
Warnings/PrecautionsCaution should be exercised in patients with history of liver and kidney disease, ketoacidosis, elderly, during pregnancy and breastfeeding It may cause drowsiness, dizziness, blurred vision or lightheadedness, do not drive a car or operate machinery while taking this medication Avoid alcohol consumption