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Why is SGPT (ALT) Blood Test Performed?

  • 4.7 (6 Votes)

SGPT is a blood test to determine the amount of the enzyme Serum Glutamic Pyruvic Transaminase in the human blood. It is performed during doubtful medical conditions of heart and liver and it is one of the effective diagnoses to evaluate liver health. A normal value of SGPT ranges from 7 to 56 units per litre of serum.

What is SGPT?

SGPT or Serum Glutamic Pyruvic Transaminase is an enzyme, which is found in heart and liver cells. This enzyme is normally inactive, however, during the condition/s of a seizure or damage, our heart or liver releases this enzyme in the blood. SGPT is also released due to the ill effects of certain medications. Also called as Alanine Aminotransferase (ALT), SGPT level is very crucial to diagnose for the proper care of heart and liver.

Uses & Benefits of SGPT Blood Test

SGPT Blood Test is beneficial to detect any or some of the following conditions

  • Heart Diseases- Coronary artery disease, cardiac arrest, congestive heart failure, arrhythmia, peripheral artery disease, stroke, and congenital heart disease
  • Liver Diseases- Hepatitis A, Hepatitis B, Hepatitis C, Cirrhosis of the Liver, Hemochromatosis etc.
  • Heart diseases affecting the Liver – SGPT Blood Test should be done during liver function tests in heart failure, cardiogenic ischemic hepatitis, congestive liver fibrosis, and cardiac cirrhosis
  • Liver diseases affecting the Heart- Complications of cirrhosis such as hepatopulmonary syndrome, portopulmonary hypertension, pericardial effusion, and cirrhotic cardiomyopathy as well as noncirrhotic cardiac disorders such as high-output failure caused by intrahepatic arteriovenous fistulae

How SGPT Blood Test is done?

This test is very simple and takes only a few minutes. It is almost like a normal blood test where a blood sample around 7 ml is taken out of your body through an injection. The collected blood is put into a tube and sent to a lab for proper diagnosis under the recommendation of your doctor.

sgpt blood test

How to prepare for SGPT Test?

Before going for a blood work for SGPT level testing, one should avoid certain medications, herbs and supplements after a proper consultation from the doctor. Also, let your doctor/medical supervisor know clearly if you have any other medical conditions such as high blood pressure, depression etc. before going for the test. You can ask your doctor if you have any queries regarding the test as well.

What are the normal SGPT Lab Test results?

Normally one has SGPT values ranging from 7- 56 units per litre of serum in heart or liver cells. If the value is higher than that, it may kill the liver or heart cells resulting in many dreadful medical situations as discussed above. Chiefly, fatty liver and prolonged cardiovascular issues are some of the reasons in the escalation of SGPT counts.

How SGPT values affect Pregnancy?

If a woman has excess liver fat during pregnancy, probably she has her SGPT level alleviated which is a point of concern for both the mother and the baby. This may lead to various situations such as Viral Hepatitis, Autoimmune Hepatitis, HELLP Sydrome, and Preeclampsia etc.

Can higher value of SGPT affect fertility?

Raised levels of SGPT enzymes are associated with infertility because the healthy reproductive system requires healthy liver. The liver helps the body in getting rid of excess toxins and maintains the hormonal balance. If the liver does not function properly, then the body can have toxins and hormonal imbalance, which can come in your way of having a baby.

sgpt affect fertility

What if my SGPT Blood Test Results are not normal?

If you are detected with high SGPT count, it is either the emergence or a prolonged condition in liver or heart. However, test results are only a part of your entire medical issue and current health. On the basis of SGPT test, your medical professional/doctor may prescribe you one or more tests, treatment and lifestyle changes whatever is necessary for the betterment of your cardiac and liver health.

How to reduce SGPT levels?

An increased amount of Serum glutamate pyruvate transaminase (SGPT) in the blood can indicate some sort of damage or illness affecting the liver. Excessive intake of alcohol, Certain medications, and health conditions such as liver cancer or hepatitis are responsible for the higher levels of SGPT enzyme in the blood. Apart from this, strenuous activities too can play a role in elevating the SGPT levels. Controlling SGPT level in the body may include:

1. Changes in Nutrition Intake

Having organic foods that are rich in nutrients helps in cleansing of the liver through the removal of toxins thereby allowing it to form new cells and stopping SGPT leakage in the blood.

2. Increased Consumption of Vitamin D

It has been established through studies that those who have increased levels of vitamin D are less likely to get liver diseases in comparison to those with lower levels. Vitamin D is known to protect the liver from the damaging conditions and diseases.

3. Avoid Fatty Foods

It is advised to steer clear of fatty foods as they make it difficult for the liver to digest the nutrients present in the food. Liver with more than 10% fat is termed as fatty liver condition. Such cells in liver cause inflammation in the liver cells that causes damages to the liver therefore increasing SGPT levels. Oily foods, red meat, processed foods, carbonated drinks, bacon etc. should be avoided to keep your heart and liver healthy and safe.

avoid fatty foods

Symptoms of high SGPT

Right from producing chemicals for normal bodily functions to acting as a storage unit and detoxifying various substances, present in the body, by breaking them down, liver has a number of functions to perform. It is possible that use of certain medications, excessive alcohol or some other factors can lead to a damaged liver and a person may show the following symptoms:

Difference between SGPT and SGOT

Alanine aminotransferase (ALT) is another name for serum glutamic pyruvic transaminase (SGPT) while enzyme aspartate aminotransferase (AST) is also known as serum glutamic oxaloacetic transaminase (SGOT). Both of these enzymes are present inside the liver. Apart from the liver, these are also present in muscle cells although in lower amounts. In case of an injury or diseases or any other kind of damage caused to the liver, these enzymes get secreted into the bloodstream marking elevated values of AST and ALT.

Cost of SGPT blood test

The cost of SGPT blood test varies from Rs. 100 to Rs. 300 depending upon the laboratory and city where the test is being performed. You can visit a laboratory and give your blood sample for the test results and also you can call a sample collector at your home and get your test reports online in a day or two. You can choose any of the above methods depending upon your convenience and suitability.

So, now you know that higher values of SGPT can impact your fertility as well as pregnancy. Hence, get your SGPT levels under control and live a happy and healthy life!

Call at +917899912611 to know about fertility treatment options available for you depending upon your medical condition.

Dr. Kavita Jaggi Agrawal

About The Author

Infertility Specialist, Obstetrician Dr. Kavita Jaggi Agrawal

Dr. Kavita Jaggi Agrawal is an obstetrician, gynecologist and infertility specialist who is providing her valuable expertise in the field of gynecology and infertility issues. She ensures that the patients receive the required fertility treatments well on time. Dr. Kavita specializes in the treatments like High Risk Pregnancy Care, In Vitro Fertilization (IVF) and Reproductive Medicine. Currently, she is practicing at Amit Jaggi Memorial Hospital, Vibhav Nagar, Agra.


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Vishnu Rana

The cost of SGPT test is economical and I am looking forward to having it. Thanks for the share Ela.

Oct. 5, 2018, 9:10 a.m. 4.5


Shivani Nayer

I have some symptoms of high SGPT like shortness of breath and swelling in legs. Does that indicate I have SGPT?

Sept. 25, 2018, 5:15 p.m. 5.0


Shayam Milan

I used these listed methods to reduce my SGPT level. In one month I was able to reduce 5 units. It's an easy and effective way to fight SGPT.

Sept. 17, 2018, 11:57 p.m. 4.5


Radhika Vikram

My SGPT level is 42 units per liter of serum. Would I be able to conceive?

Sept. 15, 2018, 4:42 p.m. 5.0


Diwakar Pathak

I was suggested by my doctor to have SGPT blood test and I came across this article by researching. All my doubts are clear now. Many thanks to Ela for sharing this.

Aug. 30, 2018, 1:02 p.m. 4.5


Subrata Chaudhry

Aug. 27, 2018, 11:44 a.m. 4.5

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