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Uses, Side Effects, Interactions and Substitutes of Regestrone 5 MG Tablet

  • 4.8 (5 Votes)

Regestrone 5 MG tablet is used in the treatment of endometriosis, breast cancer and menstrual pain. Some side effects of Regestrone Tablets are acne, hirsutism, irregular menstrual bleeding, skin reaction, weight gain and nausea. Best substitutes of Regestrone 5 MG include Gynabest, Gynaset and Covafem.

Novartis India Ltd.’s product, Regestrone 5 mg tablet is used in the treatment of endometriosis, abnormal vaginal bleeding and menstrual disorders. Active ingredient includes  Norethisterone. Regestroneis also utilized as a birth control for preventing unwanted pregnancies. It offers eight weeks contraception. Norethisterone stops the ovulation process. It also changes uterus lining for making it less likely for the fertilized egg to attach with it. It is available in the form of injection and is the convenient form of short-term contraception.

Why is Regesterone 5 MG Tablet prescribed?  

The medicine is useful in treating the:

1- Abnormal uterine bleeding- Regesterone 5 MG tablet is used for preventing the episodes of prolonged and heavy bleeding during periods.

2- Amenorrhoea- it is used for the treatment of an absence of the menstrual period in the woman of reproductive age.

3- Breast Cancer- Sometimes the medicine is prescribed for the treatment of certain types of breast cancer.

4- Contraception- For preventing unwanted pregnancies this medicine can be used as an oral contraceptive.

5- Endometrial Cancer- It helps in the treatment of several types of cancer where the uterus tissue lining grows outside and causes pain.6- Pre Menstrual Syndrome- Regesterone helps in the treatment of symptoms, which occur between ovulation and onset of the menstrual period. The symptoms include breast pain, headache, mood disturbances, water retention etc.Premenstrual syndrome

What are the substitutes for Regesterone 5 MG Tablet?

Below is the list of substitutes of Regesterone 5 MG tablet with same composition, strength and form. You can also use them by

consulting the doctor once.


1- Covafem 5 mg by Zuventus Healthcare Ltd

2- Dubogen 5 mg by Unichem Laboratories Ltd

3- Gynaset 5 mg by Mankind Pharmaceuticals Ltd

4- Norgest 5 mg by Micro Labs Ltd

5- Norglen 5 mg by Glenmark Pharmaceuticals Ltd

6- Sysron-N 5mg by Systopic Laboratories Pvt Ltd

7- Gynabest 5mg by BestoChem Formulations India Ltd

8- Prolin N 5mg by Lincoln Pharmaceuticals Ltd

9- Nostra 5mg by Corona Remedies Pvt Ltd

What are the interactions of Regesterone 5 MG Tablet?

There is always a risk of interaction when you take more than one medicine at a time or can be due to food or disease.

1- Interaction with disease:

a- Depression- Regesterone 5 MG has been reported to increase depression. Patients who have a history of depression should use this medicine with caution.

b- Fluid Retention and edema- Patients who have a fluid retention disorder or exposed to risk factors should use this medicine with caution.

c- Hepatic neoplasms- Patients who are suffering from the liver tumor are recommended not to use this medicine as an oral contraceptive. There is a high risk of adverse effects and need extreme caution.

liver tumor

d- Retinal thrombosis- this medicine can cause a disturbance in vision and other problems in eyes. If a patient has pre-existing eye disease then they should use this medicine with caution.

2- Interaction with Lab test- Inform the doctor if you are using this medicine and if thyroid function test is advised. It might interfere with the test results.

3- Interaction with medicine- There are chances of drug interaction if you are using other drugs with Regesterone tablet. With the following drugs, Regesterone may interact:

a- Cyclosporine A

b- Estrogens conjugated

c- Griseofulvin

d- Phenytoin

e- Rifampin

What are the dosage instructions for Regesterone 5 MG Tablet?

It is advised to take a missed dose immediately after noticing it. You can skip the missed ones if next's scheduled dose is close. Do not take extra doses for making up the missed doses. Consult your doctor for in schedule if you are regularly missing the medicine. Do not take more than the prescribed doses. Taking more than prescribed doses will only worsen the symptoms rather than improving them. If you notice any unwanted side effects then consult your doctor immediately.

Regesterone 5 mg tablet

What are the Side Effects of Regestrone 5 MG Tablet?

The following is a rundown of possible side effects of Regesterone tablet. These are the possible side effects and do not occur always. Some of the side effects are rare but serious. Consult your doctor if you find any severe side effect and do not go away with time.

1- Irregular menstrual periods

2- Enlargement of breasts

3- Stomach discomfort and pain

4- Weight loss or weight gain

5- Trouble Sleeping

6- Acneiform eruptions

7- Facial hair growth

8- Loss of vision or blurred vision

9- Bulging of eyes

10- Migraine like headaches

11- Difficulty in breathing

12- Presence of blood in cough

13- Sharp or crushing pain in chest

14- Dizziness and fainting

15- Weakness in arms, hands, legs or feet

16- Swelling of face, lips, eyelids, tongue, hands and feet

17- Yellowing of skin and eyes

18- Depressed mood

19- Difficulty in swallowing

20- Allergic skin reaction


To know more about Embryo Transfer and IVF, please read our article on Embryo Transfer Procedure in IVF. In case you are looking for Gynae problems then explore our article on Best Gynecologists in Delhi.


Dr. R K Sharma

About The Author

Reproductive Endocrinologist, Hysteroscopic Surgeon Dr. R K Sharma

Dr. R K Sharma has completed MBBS and MD in Obstetrics and Gynecology from Pune University in 1981 and 1989 respectively. Dr. R K Sharma is one of the pioneers in the field of IVF treatment in India. He specializes in IUI, IVF, Embryo transfer and Hysteroscopy procedures. He is also a member of Federation of Obstetrics and Gynecology Societies of India (FOGSI). Dr. R K Sharma is presently practicing at Primus Super Specialty Hospital, Chanakyapuri, Delhi. To know more, visit


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Pushkar Tilak

I have antidepression pills like Fluoxetine. What side-effects might occur to me by having both the pills together? Are they will be the listed one or something else?

Oct. 11, 2018, 1:30 p.m. 4.5


Suchitra Pradhan

The side effects of having regestrone 5mg tablets look horrible. Is it will be safe for me to have those during my contraception? Please suggest some methods to have the least side-effects.

Aug. 28, 2018, 7:45 p.m. 5.0


Karren Mathur

I get horrible cramps during periods, can I have Regestrone 5 mg tablets during the time of my periods?

June 2, 2018, 1:15 p.m. 5.0


Khushboo Joshi

I have abnormal uterine bleeding, every time I have sex. Does using a regestrone 5mg tablets provide instant relief?

May 13, 2018, 3:22 p.m. 5.0


Vivek Bansode

Feb. 8, 2018, 9:59 a.m. 4.5

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