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Dolo 650 MG Tablet - Uses, Side-effects, Composition and Dosage

  • 4.8 (7 Votes)

Dolo tablets are mild painkillers used to treat fever, arthritis, stomach pain, tooth pain and any other muscle related pain. It is composed of Paracetamol. Adults can take dolo 650 mg thrice a day while the kids can have 0.25 to 0.50 tablets twice a day or as directed by the doctor. It can also cause certain side effects such as allergy, acne or bloating.

What are Dolo Tablets?

Dolo tablet is the brand name of a mild analgesic (painkiller) which is used to treat fever and fever related pain, cold, menstrual cramps or period pain, toothache, joint pain (arthritis), headache, stomach pain or any other operative pain elements. Sometimes, it is also prescribed to the people with cancer to help them in getting some relief from the pain.

The medicines can be taken during pregnancy or breastfeeding also but only under the guidance of a medical practitioner.

Dolo 650 MG is taken orally or rectally depending on the severity of the issue.

Composition and Nature of Dolo 650 MG

Dolo 650 MG tablet is mainly composed of active salt i.e. Paracetamol (strength: 650 MG, which acts as an active ingredient scientifically known as Acetaminophen). Paracetamol is commonly used to treat, manage, prevent and improve fever and pain including fever pain, toothache, cold, flu, ear pain and menstrual period pain. Micro Labs Ltd manufactures Dolo 650.

Dolo is a safe mild medicine for short time use. It is analgesic, which helps, in relieving pain and antipyretic medicine that reduces fever. So anyone experiencing fever with muscle cramps or menstrual periods with unbearable cramps can take Dolo tablets with strength of 650 MG. For period specific cramps you can always explore the natural ways and remedies. Some of the effective ones are listed here in our article on Home Remedies for Period cramps.

Dolo Tablet - Onset of Action & Duration of Effect

If the medicine is consumed to reduce fever, then it takes around 30 minutes to start its action. Otherwise, if consumed for relief in pain, it can take around an hour after the administration to get some relief.
The effect of the medicine remains in the body for around 4-6 hours after which another dose needs to be taken if the pain or fever is not reduced or controlled.

1. Category of Dolo tablet

OTC– Although Dolo 650 falls under OTC (Over-the-counter) drugs category but still you should get it prescribed by your doctor.

2. Dolo 650 MG Tablet – Price & Expiry Date

One strip of Dolo 650 MG tablet contains 15 tablets costing Rs. 33.46. Expiry duration of the tablet is mentioned on the strip itself. Please refer to the strip for more details about the expiry date.

Uses and Benefits of Dolo 650 MG

Dolo 650 MG is prescribed to cure, treat and prevent pain which is mild in nature. If you are planning to consume Dolo 650 MG during severe pain, you should consult your medical professional for additional medicine or an extra dose of Dolo 650 MG.
Dolo 650 mg joint pain relief tablet

Normally, Dolo 650 MG is prescribed to treat below conditions -

  • Dysmenorrhea or Menstrual pain. To get relief from Menstrual pain, you can also use Regestrone 5mg Tablets. 
  • Feverish chills and pain
  • Muscle and Joint pain such as Arthralgia (pain in joint) and Myalgia (pain in muscle)
  • Ear pain and Toothache
  • Headache including Migraine
  • Stomach Pain

Dosage Information for Dolo 650 MG

Dolo 650 MG dosage varies depending on the patient’s age and severity of the issue. 

  • For an adult: Dolo 650 mg can be taken thrice a day. If prescribed by the doctor, dolo 650 tablet can be taken after every 4-6 hours depending upon the patient’s health. 
  • Maximum Dosage: Maximum dosage is 4 grams in a day. Do not exceed this limit. Otherwise, it can be fatal.
  • For children: Dolo 650 MG is suggested from 0.25-0.50 tablets twice a day depending upon the weight of the kid. 

However, if you are consuming Dolo 650 MG for operative pain (Laparoscopy i.e.), a detailed consultation with your medical professional/doctor will be useful. Normally it is consumed after food, as consuming Dolo 650 MG in the empty stomach can cause acid reflux. For better results, swallow Dolo 650 MG with water. Please make sure not to chew, crush or break it before consumption.

Dolo 650 MG- Side-effects

Dolo 650 MG is a very effective tablet to relieve mostly all sorts of pain in the body and comes under mild to light medication category. However, it is not completely free of side effects. Some of the possible side effects of Dolo 650 MG are -

Vomiting and Food aversions

  • Infection and swelling of skin including skin rash and reddening of the skin
  • An overdose of Dolo 650 MG can lead to permanent damage of the liver
  • Vomiting and Food aversions
  • Dizziness and Nausea are two of the often spotted side effects of Dolo 650 MG
  • Abdominal pain and discomfort
  • Abnormalities in blood cells and blood cells count
  • Blisters and Acne
  • Breathing and Visual problems
  • Nasal tract infection/s
  • Gas, Heartburn, and Bloating  
  • A very rare condition i.e anemia can also be caused due to the overdose of Dolo

Visit your doctor immediately, if you experience any of the above-mentioned side effects.

Risks & Precautions of Dolo 650 MG

Although Dolo 650 MG is an OTC (Over the Counter) product, it is always better to consume it after a doctor's prescription.

People with lung problems

Avoid consuming Dolo 650 MG under following conditions such as:

  • If you are detected with Thyroid or undergoing treatment for Thyroid. In case you are looking for the treatment of Thyroid, then do read our health article on Inositol Supplements.
  • People allergic to Paracetamol should avoid consuming Dolo 650 MG.
  • If you have a high blood pressure you should restrain yourself from consuming Dolo 650 MG. 
  • People with lung problems should not consume Dolo 650 MG.
  • Pregnant and lactating mother should take prior advice from Doctor/Medical Supervisor regarding consuming Dolo 650 MG. A Pregnant woman should never stress up and always consult a doctor for any type of medications. For more insights, read our article on How Stress Affects Pregnancy.
  • People with prostate enlargement issue should restrain using Dolo 650 MG.
  • Age Limit for Dolo tablet: Children below 10 years and old people above the age of 70 should not consume Dolo 650 MG as it may lead to high blood circulation issues.

Substitutes for Dolo 650

Following substitutes have the same salt composition and strength as of Dolo 650. Paracetamol 650 MG is the main active ingredient in Dolo as well as in the below-mentioned tablets.

  • Welset 650 MG tablet
  • Parafizz 650 MG tablet
  • Paarmol 650 MG tablet
  • Cipmol 650 MG tablet
  • Glenpar 650 MG tablet

Dolo 650- Frequently Asked Questions (FAQs)

1- Is it safe to Take Dolo 650 MG during pregnancy?

One is advised to take prior medical help with the actual status of pregnancy before consuming Dolo 650 MG.

2- What happens with the overdose of Dolo 650 MG?

If you happen to overdose Dolo 650 MG, please rush to your nearest medical center or healthcare provider for help. Otherwise, it can lead to rigorous vomiting, blood pressure or in extreme cases multiple organ failures.

3- Can Dolo 650 MG be taken with Ibuprofen?

Yes. Dolo 650 MG can be taken with Ibuprofen as both help in relieving pain and fever. But, people with Irritable Bowel Syndrome (IBS) should avoid taking Dolo 650 MG with Ibuprofen as together they can lead to acid reflux and gastrointestinal problems.

4- Can Dolo 650 MG be prescribed to people with Allergic issue/s?

No. Dolo 650 MG can escalate the level of already existing allergic symptoms in a human body. People with skin infection issues and hypersensitivity should avoid consuming Dolo 650 MG.

5- Which is better Dolo 650 or crocin?

Dolo has a higher strength of paracetamol 650 MG as compared to Crocin which contains 500 MG of paracetamol. Both the medicines have the same composition. The main difference between Dolo and Crocin lies in their brands and strength.

6- Can I take Dolo 650 with alcohol?

No. It is not advised to take Dolo 650 medicine with alcohol. It can cause damage to the liver. 
SGPT test is done to identify issues in the liver. To know more about this test, read our article on SGPT test.

7- Is Dolo 650 good for headache?

Yes. Dolo is a very effective medicine for headache. It starts showing its effect within one hour. There should be a gap of at least 4 hours before taking the next dose.

8- Is Dolo 650 effective in joint pain?

Dolo is an effective tablet for mild joint pain. It is a mild anti-inflammatory medicine and may not work for severe joint pain. A person has to consult a doctor or take over the counter NSAID (Nonsteroidal Anti-inflammatory Drug) for joint pain relief.

9- Can Dolo result in weight loss?

Dolo does not result in weight loss and is used for short-term only. It can have some other side effects like skin allergies and low blood pressure.

10- Who should not take Dolo?

Persons who have severe liver disorders should not take Dolo 650 as it can further increment the condition. Also, people who had allergies in the past with this tablet should avoid it and replace it with a substitute.

11. Is Dolo a painkiller?

Yes, Dolo is a painkiller which is consumed to get relief from pain. It is also used to lower down the fever.

12. Is Dolo 650 safe to use?

Dolo 650 MG is absolutely safe to use for the short term as recommended by your physician. Do not take overdose or also try to avoid if you have allergies or liver impairments. 

13. Can Dolo cause drowsiness?

Dolo 650 can cause drowsiness. Therefore, it is suggested to take some rest after consuming the tablet.

14. Is Dolo tablet banned?

Dolo 650 MG is not banned in India, US and Japan. It is readily available in these countries. Certain tablets such as Dolo Cold, D Cold Total and Vicks Action 500 are banned in India because of their side effects and harmful composition.

15. Ibuprofen vs Paracetamol

Both Ibuprofen and Paracetamol based drugs are analgesics (Painkiller). But their action mechanism is different. Paracetamol gives relief from pain and also reduces fever. While Ibuprofen provides relief from pain and fever but it also helps in controlling inflammation.

16. Can I take expired Dolo 650?

The effect or action of expired tablets is not guaranteed. Moreover, it may cause some serious side effects. Therefore, it is always better to avoid expired tablets.

To know about home remedies and natural ways to treat Viral Fever please read our article on Natural ways to treat Viral Fever and in case you are suffering from a high degree of Fever coupled with stomach pain then explore our article on Ketoral DT tablets.

Dr. R K Sharma

About The Author

Reproductive Endocrinologist, Hysteroscopic Surgeon Dr. R K Sharma

Dr. R K Sharma has completed MBBS and MD in Obstetrics and Gynecology from Pune University in 1981 and 1989 respectively. Dr. R K Sharma is one of the pioneers in the field of IVF treatment in India. He specializes in IUI, IVF, Embryo transfer and Hysteroscopy procedures. He is also a member of Federation of Obstetrics and Gynecology Societies of India (FOGSI). Dr. R K Sharma is presently practicing at Primus Super Specialty Hospital, Chanakyapuri, Delhi. To know more, visit


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Deepak Jaiswal

Can I take Orofer XT to increase the hemoglobin? Please suggest.

Oct. 3, 2018, 8:23 a.m. 5.0


Niraj k Rawal

Today when I was at the gym I slipped my leg and fell down on my butt. It is paining now and feeling like some fever. Can I use Dolo 650 to get relief from pain and avoid fever?

Aug. 13, 2018, 7:21 p.m. 4.5


Punit Pradhan

I am suffering from a headache. Can I use Dolo-650 Tablet?

Aug. 13, 2018, 2:18 p.m. 5.0



My doctor prescribed me with dolo 650 mg tablet for my fever. After reading this article I got many points about this medicine. Thanks for sharing.

July 31, 2018, 12:14 a.m. 5.0


Pradeep Mehta

I really felt tired and weak after having Dolo 650 tablets. It is better to take crocin or paracetamol rather than Dolo for me.

May 12, 2018, 3:05 p.m. 4.5


Priya Goragandhi

Dolo 650 mg tablet is a paracetamol drug containing tablet and cures normal headache, toothache, arthritis and backache. Though it's a paracetamol you need to avoid excess intake of alcohol while taking dolo, especially if you're planning a baby. Alcohol and dolo can affect your liver.

Oct. 28, 2017, 12:01 p.m. 4.5


Suganya Banerjee

Dolo 650 mg is really useful in cases of menstrual pain, tooth ache, some cases of migraine as well as joints pain. You must consult your physician or concerned physician before consuming the medication.

Oct. 28, 2017, 12:01 p.m. 5.0

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