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    pink loader
    in vitro fertilisation (ivf)

    Preimplantation Genetic Diagnosis - Procedure and Benefit

    • 4.8   (6 Votes)
    Medically Reviewed by Dr. Kavita Jaggi Agrawal - MS, MBBS on 30 Mar 2019 - Written by Dr. Deepika Tiwari - MS, MBBS - Grammatically Approved by Dr. Sailaja Vuppu - MBBS, CCT, MRCOG

    Preimplantation Genetic Diagnosis is a procedure used before implantation to identify genetic defects within embryos. Therefore the PGD or PGS procedure is done before embryo transfer during an IVF cycle. The benefit of PGD is that it detects defects in embryo before its implantation in uterus.

    Preimplantation genetic diagnosis is a procedure, which is used to identify genetic defects in embryos, which are created through IVF procedure before pregnancy. (1) However, the main advantage of Preimplantation genetic screening is to avoid selective abortion, as the method makes the embryo free of all diseases. (2)

    The article will let you know about:

    1. What is the procedure of Preimplantation genetic Diagnosis?
    2. What are the benefits of Preimplantation genetic Diagnosis?

      1.  What Is the Procedure of Preimplantation Genetic Diagnosis?

      In order to perform PGD procedure, pre-embryos must be available for screening. The patient has to go through a regular IVF cycle. (4) PGD or PGS procedure is usually processed after the collection of eggs from the ovaries followed by the fertilization process. The PGD procedure involves various steps:

      • Five days developed cells are removed micro-surgically from the embryos. After this process, the collected embryos are then frozen. (5)
      • The DNA of the cells is then evaluated to determine if any defect is present in embryo. PGD process can take at least seven days. (5)
      • Once Preimplantation genetic diagnosis procedure has identified embryos free of genetic problems then the embryo will be implanted into the uterus. (5)

      2.  What Are the Benefits of Preimplantation Genetic Diagnosis (PGD)?

      There are multiple benefits of PGD or PGS process which are mentioned below:

      • Preimplantation genetic screening is done for single gene disorders to avoid their transmission. (6)
      • PGD later reduces the requirement for amniocentesis in pregnancy. (4)
      • It ensures the implantation of the selected or tested pre-embryo. (4)
      • PGS reduces the risk of multiple pregnancies. (7)
      • The screening procedure identifies abnormalities in embryos and also prevents unhealthy embryo from being transferred into the uterus. (7)
      • PGS or PGD procedure is performed before embryo implantation thus it allows the couple to decide if they wish to continue with the pregnancy or not. (5)

      Preimplantation Genetic Diagnosis

      Egg Fertilization during Preimplantation Genetic Diagnosis (PGD) will be done either by:

      Apart from reading interesting blogs, you can also know about various infertility treatments such as IVF, IUI, ICSI, TESA, MESA, and Surrogacy by visiting our official website or else you can contact us on +918929020600 and speak to our fertility specialist.

      Dr. Deepika Tiwari

      Written by

      MS, MBBS

      Dr. Deepika Tiwari is a talented Gynecologist, Obstetrician and Infertility Specialist based in Sector 54, Gurgaon. She has over a year of experience and has helped thousands of women go through pregnancy without any complications.
      Dr. Deepika Tiwari is an expert obstetrician with specialization in Normal Vaginal Delivery (NVD), Woman Health-check, Gynae Problems, Infertility Evaluation/Treatment, Pap Smear and Laparoscopic Surgery (Obs & Gyn).
      She attained degrees in MBBS and MD in Obstetrics and Gynecology from Sir JJ Hospital, Mumbai, and passed out with top ranking results. She excelled in her academics and went on to train in many reputed hospitals and institutions.
      She is a very passionate doctor, exhibits a high degree of professionalism, and work ethics. Dr. Deepika Tiwari is among the best Gynecologists in the city and is widely respected and trusted by her patients, and colleagues alike. She is a proud member of the Federation of Obstetric and Gynecological Societies of India (FOGSI) and an Active Participant In Regional and National Obstetric & Gynecology Conferences and Workshops.
      Dr. Deepika follows the best practice guidelines as per international protocols of Gynecologists & Obstetricians. She is best known for her dedication to patient care and promoting normal delivery. Presently, Dr. Deepika Tiwari is practicing her expertise at HCL Healthcare Clinic, Sector 54, Gurgaon and Cloudnine Clinic, Sector 56, Gurgaon.
      HCL Healthcare Clinic is one of the most visited multi-specialty clinic situated in Gurgaon. This Clinic is set-up in affiliation with Johns Hopkins Medicine International, therefore, meet all the medical standards.
      The centers focus on the vision to deliver the highest standard of healthcare and which is why it is one of the best infertility clinics in Gurgaon. By gaining years of experience, they are offering unparalleled treatment to patients from all around the world. The dream of having a baby is made possible in this clinic as they offer an array of services like Micro Epididymal Sperm Aspiration (MESA) and In Vitro Fertilization (IVF).





      Abhisekh Kripalani

      PGD is the best option for the couples who cannot conceive and have miscarriages but this method shouldn't be used as gender selection process.

      Oct. 11, 2018, 1:13 a.m. 4.5


      Sujata Baxi

      I never knew these options are available for the couples. It was knowledgeable, thanks for sharing.

      Oct. 7, 2018, 6:08 p.m. 5.0


      Pulkita Rathore

      What if I don't produce healthy embryos, does the treatment will fail or we have some other options too?

      Oct. 5, 2018, 4:10 p.m. 4.5


      Jigyasa Rawat

      My three pregnancies resulted in a miscarriage. Now, I am considering PGD IVF to have my child.

      Oct. 4, 2018, 9:51 a.m. 5.0


      Karishma Negi

      My husband has a genetic disorder in my eyes. I think we should also opt for PGD to complete our family.

      Oct. 4, 2018, 4:32 a.m. 5.0


      Vrajakishore Giridhara

      Oct. 3, 2018, 11:57 a.m. 4.5

      View all comments

      Leave a Comment



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      It is not advised to self-diagnose or treat any medical condition or disease following the information given in this article. We insist you to consult a registered practitioner and never try to replace their advice or discontinue treatment in between by relying solely on the information obtained. External links to different websites as well as videos given on the website serve the purpose of sharing knowledge only. Ela being an Independent Medical Information platform is neither responsible nor guarantees the authenticity, reliability, and accuracy of these videos and websites in any way. We do not intend the information displayed here to be used for a medical emergency, if you seek medical attention for yourself (or any other person with whom you want to share the information with), we advise you to directly get in touch with the hospital or the doctor.

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