Fertility treatments in India are comparatively more affordable and have high chances of success when compared to most of the other countries across the world. Most of the patients from all over the world visit India in the hope of successful treatment at a cost that they can afford. Becoming parents is like a blessing, but not everyone is in the state to spend a large amount on that. These days it has become much easier for the patients to get access to top quality infertility treatments. This is all because of the developing advancements in the field of infertility medicine. Yet, couples must research well with the help of trustworthy healthcare platforms which serve patients in the best possible manner. (1) The research should include the benefits and the success rate of the treatment that they are opting. This will help in the successful execution and completion of the chosen treatment. In this article, we will look at: What is infertility and how does it affect someone? What are the major infertility problems treated in India? What is IVF and its success rate in India? What is IUI and its success rate in India? What is GIFT and its success rate in India? What is ZIFT and its success rate in India? What is ICSI and its success rate in India? What is IMSI and its success rate in India? Reasons to Choose India for Fertility Treatments: 1. What is infertility and how does it affect someone? Infertility affects someone both emotionally and physically. It has very adverse effects and brings devastating life crisis that has a significant impact on family relationships, overall health, job performance, and social interactions. In today's lifestyle, there are many factors that contribute to increasing infertility cases like stress, obesity, sedentary lifestyle, changes in eating habits, pollution, and several others. As per the estimates are given by the World Health Organization (WHO), 48.5 million couples worldwide experience infertility. (2) Infertility is basically the condition of the male or female reproductive system that stops the couple from getting pregnant naturally. In some cases, the extended family of the person suffering from infertility also get affected. With advanced technology, infertility can now be successfully treated irrespective of the case type. India serves as a fertility tourism hub for the patients around the world and provides an affordable, world-class and professional medical care. Apart from other qualitative treatments of infertility, India is also the most preferred destination for Assisted Reproductive Technology (ART). (3) India has made its position as one of the most promising infertility treatment destinations for a wide range of international tourists. Fertility treatments in India are in their budget and also available with high international class surgical facilities which can be booked with quick medical appointments. They also provide medical care and service operations at the hands of experienced fertility experts that attracts many patients and infertile couples from different parts of the world including USA, South Africa, Europe, Canada, and East Asia. India has some of the most modern and advanced centers for infertility evaluation. They establish reproductive health and assisted fertilization services in the country today where patients are the priority. Fertility treatment in India is provided in a caring, relaxed and supportive environment. They understand well regarding the sensitive emotions involved in the fertility treatment and ensure complete privacy during and after the treatment. Today, India is the home to world-class doctors and international standard hospitals. The success rate of fertility treatments in India is also comparatively high. All kinds of fertility treatments are completely legal in India. The patients from outside the country will not have to deal with any legal complications afterward. One can easily find the best fertility doctors and centers in India. The role of good fertility experts is very important to make treatment successful. 2. What are the major infertility problems treated in India? India is known for providing the best fertility treatments to couples who are struggling to have their own babies in a natural manner. They ensure that the patient gets a successful treatment that too without wasting their hard earned money. It is good news for childless couples that fertility clinics situated in India are specialized for treating every type of infertility problem. They ensure to provide the best facilities for a wide range of fertility treatments to help childless couples receive top quality complete treatment under one roof. Some of the infertility issues resolved in India are women with blocked or damaged fallopian tubes, ovulation problems, issues related to sperm count, quality, endometriosis or men with low sperm motility. (4) Fertility Treatments Offered in India: A wide range of factors makes an environment that contributes to positive outcomes, making India one of the largest fertility tourism hubs in the world. Fertility doctors in India contribute the most part in making any treatment possible and successful. However, one question that most people have about fertility treatment in India is exactly what the country offers, that makes it a hotspot for fertility treatments. Let’s have a look at some of the fertility treatments, which India has to offer: 3. IVF or In Vitro Fertilization Treatment in India: IVF treatment in India has gained a lot of popularity around the globe for the high success rate with respect to the occurrence of pregnancy. IVF treatment in India is performed by infertility specialists who have qualified in the field of embryo culture and genetics. Advanced tools and modern laboratory equipment is used to perform the treatment. The embryos are developed in contamination-free medical labs with extreme care under the expertise of an experienced embryologist. After the embryos reach a suitable stage, they are transferred to the uterus at the exact time of ovulation. The further process takes place inside the uterus of the woman. In Vitro Fertilization in India has become a blessing in the life of infertile couples to have their own baby. Most of the fertility doctors in India are famous worldwide for their success rates. (5) Benefits of IVF treatment: IVF treatment in India has given hope and opportunity to many infertile couples looking for infertility treatments. Here are some of the reasons why infertile patients from all around the world prefer IVF treatment in India: IVF treatment in India is affordable and has a high success rate Women suffering from PCOS, endometriosis or blocked fallopian tube can go for IVF Intended parents with unexplained infertility can choose IVF treatment in India IVF is also helpful in cases of ectopic pregnancy or miscarriages In Vitro Fertilization (IVF) Success Rate in India IVF has a high success rate as compared with other fertility solutions. However, this success rate depends on many other factors as well. The success rate of IVF treatment is inversely proportional to the age of the female partner. With the increase in age the IVF success rate decreases. For example, the women who aged more than 35 years have 40.7 % success rate and it is only 3.9 % for women who are more than 42 years old. Apart from this, the success rate also depends on other factors such as reproductive history, cause of infertility, and lifestyle factors. (6) 4. Intrauterine Insemination (IUI) Treatment in India: IUI treatment in India is done with extreme care and precision. It is generally performed when the sperms of the male partner are not sufficient enough or have low motility to conceive naturally. Both the partners go through multiple tests to determine the exact cause of treatment. (7) Once the cause is diagnosed, the doctor provides stimulating drugs to the woman to stimulate ovulation. Highest quality sperm samples are taken from the male partner and inserted into the uterus using a catheter tube. IUI procedure is performed by highly experienced fertility doctors in India. Benefits of IUI procedure: The procedure of IUI is basic infertility treatment. Here the sperm is inseminated into the woman’s body and left fuse with the egg in a natural way IUI is less complicated than other infertility treatments IUI is also a very cheap process. It costs much lesser and almost one fourth the price of an IVF cycle In cases of male fertility, IUI can work with a good success rate IUI Success Rate in India: Age affects fertility and in the same way, it affects success rates of IUI procedure. As with most fertility procedures, IUI success rate is higher for younger women. The chances of successful conception after one IUI cycle are 10 - 20 percent for women under the age of 35. For women between 35- 40 years of age, chances are only 10% and for women above 40, the chances are only 2 - 5 percent. The good news is that most people that try IUI will have a good chance of receiving the news of pregnancy over time. However, they might have to undergo repeated IUI procedure multiple times. It may take between 3 to 6 IUI cycles before pregnancy occurs in regular cases. If one has tried IUI for 3 to 6 cycles and have not got pregnant yet, it is time to discuss other options with the best fertility doctors in India. 5. Gamete Intrafallopian Transfer (GIFT) Treatment in India: GIFT it is the modified version of In Vitro Fertilization in India. Sometimes when the cause of infertility is minor, GIFT treatment is performed. The procedure is done by just sperm and eggs together before being inserted. The fertilization takes place inside the fallopian tube. Fertility doctors in India perform this procedure with careful actions to achieve a successful pregnancy on the first try. IVF treatment is a long and time-consuming procedure but GIFT procedure is fast and performed quickly. (8) Benefits of GIFT procedure: In the GIFT procedure, delivering a baby is as natural as possible. Women prefer GIFT to IVF treatment because fertilization occurs in their bodies rather than the medical laboratory. GIFT does not increase a woman's chances of developing ovarian cancer, as was believed until recently. GIFT is also an affordable fertility treatment in India as compared with other expensive infertility treatments. It is a convenient method as it does not require hospitalization or any extensive fertility treatment related workout. GIFT Success Rate in India: The success rate of the GIFT procedure is dependent on age and health conditions. On average, 25 - 30 % of the couples succeed in conceiving using this method. Women who are young and in good health, stand a better chance of achieving success. Even if the procedure is not successful the first time, the process can be repeated with some of the improvements, and the chances of success would not diminish. It is to be noted that if an older woman manages to produce a satisfactory amount of eggs, she stands the same chance to conceive successfully like that of a younger woman. 6. Zygote Intrafallopian Transfer (ZIFT) Treatment in India Zygote Intrafallopian Transfer (ZIFT) is one of the advanced types of infertility treatments in India. In this procedure, the fertilized eggs are transferred directly into the fallopian tube instead of the uterus. In India, the treatment is performed with laparoscopic surgery that allows doctors to reach up to the fallopian tubes of the women. Sometimes, stimulating drugs are given to the patients to induce ovulation so that the procedure can be effectively progressed. (9) It is performed in special medical laboratories to prevent any kind of infections and bring in the desired results with respect to the success of the respective treatment. Benefits of ZIFT: The various benefits of ZIFT infertility treatment in India are: Those couples who have extreme infertility issues can think of this strategy as a help to have their baby. The best aspect about this technique is that the specialist can affirm the treatment of egg before inserting it in the fallopian tube. In this way, the specialist will just choose the best and splendidly created zygote. This strategy functions admirably on those couples who have attempted no less than one year to conceive normally and have 5 to 6 fizzled cycles of IUI. ZIFT Success Rate in India: The success rate of ZIFT varies as per the age and fertility problem of the couple. Younger women have healthier eggs and high success rates. With the help of ZIFT procedure, women have a 22 % chance of delivering a baby. It is almost similar to the IVF success rate. 7. Intracytoplasmic Sperm Injection (ICSI) Treatment in India: ICSI in India is performed following an advanced procedure under the guidance of an ICSI expert. First, the eggs from the woman and sperms from the man are retrieved and kept in separate lab dishes. Donor eggs and sperms are also used in some cases. Each egg is inseminated with sperms to achieve fertilization. Only the most viable and healthy embryos are transferred to a woman’s uterus to improve the chances of success. The success rate of ICSI in India goes as high as 80 percent as the fertility doctors in India are truly dedicated and medically skilled in helping infertile couples have a baby. The doctors also provide counseling services on prevention and treatment of infertility. (10) Benefits of ICSI: Intracytoplasmic Sperm Injection (ICSI) offers the intended parents a chance to have a baby, even with severe male infertility issues. ICSI benefits include helping one get pregnant even if they are dealing with one or more of the following conditions: Low sperm count Physical blockage Poor sperm motility or morphology Having tried IVF without success The desire for pregnancy post-vasectomy ICSI Success Rate in India: The success rate of ICSI is related to IVF procedure as well. ICSI is used with conventional IVF to increase the success rate. The success rate of ICSI also depends on age. The younger you are, there are more chances of your ICSI treatment to be successful. The success rate is 44 % if you age between 18 to 35 years. It goes on decreasing and be just 11 % if you are between 43 to 45 years old. 8. Intracytoplasmic Morphologically Selected Sperm Injection (IMSI) Treatment in India Fertility centers in India perform IMSI treatment in a well-equipped laboratory. During the procedure, eggs of a woman are retrieved followed by retrieval of sperms from the male partner. It is mainly performed in cases when the sperm shape and quality of sperms are not ideal for fertilizing the eggs or when the sperms have the possibility to cause abnormalities in babies. In India, the specialized embryologists examine each and every sperm under a powerful microscope to sort high-quality sperms which are to be injected into the eggs. (11) The chances of miscarriage are low when the treatment is performed by fertility doctors in India. Benefits of IMSI: The various benefits of IMSI include: Men with sperm demonstrating a high degree of DNA fragmentation or teratozoospermia, conditions that often accompany oligoasthenospermia can go for this treatment Patients with previous failed cycles of IVF or ICSI Couples dealing with unexplained infertility can be benefitted from IMSI. It has been noticed that IMSI results in better egg fertilization rates, better rate of blastocyst formation, better quality embryos, and therefore better pregnancy rates Couples experiencing recurrent IVF failures or recurrent biochemical pregnancies and miscarriage can go for IMSI IMSI Success Rate in India: IMSI is considered to be a successful treatment in India. The overall pregnancy rate in the IMSI group was 34%. Implantation rate after IMSI was 30%. Live birth rate after IMSI was 29.6%. This success rate also depends on the age of the intended parents and the quality of eggs and sperms. 9. Reasons to Choose India for Fertility Treatments: India is the best preference for fertility treatments and the reasons for this are so many. Every year, patients from different parts of the world visit India for treatments. Here are the main reasons why India is the hub for fertility treatments: Affordable Treatments: The cost of fertility treatment in India is almost one-third of the cost of fertility treatment in other countries especially the developed ones. The reason for this being the efficiency of doctors conducting procedures. By efficiently using equipment they minimize cost and reduce treatment and recovery durations, fertility clinics in India cater to a wide range of patients from all over the world. (12) High-Quality Equipment: India has access to advanced equipment that is both, efficient and accurate. This allows for better success with treatments, owing to stellar technical expertise. India currently has the best access to the latest equipment in the industry than equipment to treat infertility in other western countries Certified Experts: The top fertility clinics in India have specialists who are renowned experts in their respective fields of medicine. They use their years of experience to ensure that each patient gets the best chance of success with fertility treatments in India Exclusive Services for International Patients: Fertility clinics in India specifically work towards catering to patients from across the globe. Marketing of fertility tourism is done, with clinics advertising their international cuisines and foreign translators. This greatly helps attract more patients opting for fertility treatment in India. Tourist Destination: India has a rich heritage and a colorful local culture, which is explored by tourists every year. Fertility tourism works like killing two birds with one stone, as patients get affordable high-quality treatments, and can also tick off exploring one more country off their bucket list. Patient-oriented Treatments: Treatments that cater specifically to patients, and put the needs of the patients first, rather than bureaucratic paperwork and legal measures are sure to be more attractive to patients opting for fertility tourism. India’s IVF treatment methods work towards being more advantageous than the healthcare system in Australia. Cutting-Edge Technology: India has access to the most advanced medical technology and the latest equipment. The hospitals are also equipped with modern devices and tools to perform fertility treatment in India with precision. These advanced treatment methods allow clinics to achieve a high success rate in IVF treatments and promote safe and ethical treatments. Non-Restrictive Laws: The fertility guidelines in India do not restrict egg or sperm donation, fertility preservation, assisted techniques or genetic testing. There are no legal documents required by fertility clinics in India to perform the treatment. This makes it ideal for couples suffering from severe infertility, who need a boost in the right direction. Most of the international patients choose to visit India for treatment for this same reason. No Language Barrier: The fertility specialists and consultants in India speak English, which allows patients to understand each aspect of their infertility treatment. The fertility doctors in India give their best to explain the cause, diagnosis, and treatment to every patient. The fertility tourism sector is increasing every day, with a catered range of treatments that focus on putting the needs of the patient first and delivering success rates that are the best in the industry. With the revenue from the field of infertility treatments, tourism is expected to get triple by 2020, there is no doubt, this industry is proving to be a boon to India’s economy, as well as patients across the world. India has a lot to offer to medical tourists coming from across the world for fertility treatments. Over the years, India has emerged as one of the fastest growing countries for fertility tourism giving infertile couples a chance to become parents with the highest standard of treatments. With so many benefits for patients, India is the new hub of fertility treatment. Reproductive healthcare facilitators like Elawoman can help you get the best treatment in India without facing any difficulty. From finding an ideal hospital to providing medical loans, Elawoman stays by your side throughout your treatment. You can contact Elawoman at +918929020600 for any assistance for your treatment or to book a FREE appointment with one of the best infertility treatments.
Despite the number of couples who manage to conceive without any issues, there are a number of other couples who struggle with infertility. Around one in 10 couples in the US have problems with infertility, a significant percentage. (7) Some of the causes of infertility are well-known by most people: it is a known fact that women find it harder to conceive as they get older and that certain health conditions can cause infertility. However, there are a number of factors which can contribute to infertility, which are less well known. Take a look at these 6 factors that cause infertility which you probably didn’t know about. (8) (9) 1. Untreated STDs You probably didn’t realize that one of the main causes of infertility in both men and women is untreated sexually transmitted diseases (STDs). Specifically, chlamydia and gonorrhea are leading causes of infertility, which can affect both genders. These diseases often go unnoticed because they can be asymptomatic, particularly for men with chlamydia, or may manifest only in minor symptoms which are ignored. However, even when symptoms do not present, these conditions can cause infertility when untreated. (1) It is important to regularly get tested for STDs if you are in a risk group. If you suspect you may have an STD, see your doctor for a test, particularly if you want to try for a baby, but in all cases, it is a good idea to get tested. If you find you have chlamydia or gonorrhea, the treatment is relatively straight forward: your doctor will simply prescribe a course of (specific) antibiotics in most cases. 2. Hormone Imbalance Hormone imbalances play a significant role in infertility. In fact, in most cases, hormone issues will be either a contributing factor or the main reason for infertility. Hormones are vital because they control essentially every process which happens in our bodies, and reproductive processes are no exception. In fact, reproductive processes are extremely complicated, and therefore a number of hormones are involved. This means that an imbalance in any of these hormones could adversely impact on fertility. (2) If you suspect that you are suffering from a hormone imbalance, or if you are struggling with infertility and are not sure why it could be worth having your hormone levels tested. You can arrange to perform a simple hormone test at home through a service. This usually involves a saliva test which you can do yourself, and then you send off to the lab for results. If the results show a hormone imbalance, take these results to your doctor and discuss recommended courses of treatment. (10) 3. Smoking If you smoke cigarettes, you probably already know that it is having devastating effects on your general health. But did you know it could also be making you infertile? In men, smoking has been shown to decrease sperm mobility by up to 13%, which can hinder chances of conceiving. Smoking has also been shown to impact on hormone levels, which we already know can adversely affect fertility, as well as damaging sperm in ways that can hinder fertilization, embryo implantation, and embryo development. (3) Smoking cigarettes can also affect female fertility. Not only does smoking during pregnancy leads to abnormal fetal development (as has been well-publicized), but it can stop you from getting pregnant in the first place. Smoking can contribute to problems conceiving in a number of ways, including, through causing damage to the fallopian tubes, changes to the cervix, damaging egg development, as well as increasing the risk of miscarriage. 4. Damage to Sperm DNA In 2012, new research was released which showed a new cause of infertility which could be responsible for unexplained infertility in up to 80% of couples. The study showed that damage to DNA in sperm can cause infertility if found in high enough concentrations. Damage to less than 15% is considered normal and is unlikely to have any effects. However, once that damage covers 25% or more, this can adversely affect male fertility. The findings are important because they mean that fertility treatments can be specifically tailored to couples suffering from this condition. (4) 5. Celiac Disease Celiac is a relatively well-known condition, which involves an auto-immune reaction to gluten. What most people don’t know, however, is that celiac may also be related to the incidence of infertility. This is usually an issue when the disease is undiagnosed and untreated: studies have found that undiagnosed celiac disease may cause up to 4% of unexplained infertility cases. The reason for this is still not entirely clear, but may be linked to intestinal damage or iron deficiency anemia, both symptoms of celiac disease. (5) 6. Environmental Toxins Believe it or not, but the chemicals in our environment may also be a cause of infertility. There is evidence that environmental toxins could cause infertility in both men and women. In men, these toxins are believed to impact on semen quality, making it more difficult to conceive. In women, toxins in the environment most likely impact on a range of factors influencing fertility. As part of our modern lifestyles, we are exposed to toxins through processed foods, contaminated water, as well as chemicals found in hair and beauty products. Although the evidence is still not clear on the relationship between environmental toxins and infertility if fertility is a concern it may be worthwhile avoiding these toxins as much as possible. (6) The inability to become pregnant is very difficult to deal with and can impact every aspect of life. Infertility is a common problem today but it can be overcome with the help of treatments like IVF, IUI, ICSI, and GIFT. The options that are best depend on one’s personal health condition and the cause of infertility, For the latest fertility news, tips and updates, follow Elawoman blog. Elawoman can assist you to reduce the stress associated with infertility from a medical, emotional, and financial perspective. Elawoman has helped thousands of infertility patients realize their dream of becoming parents. Our services can enhance your chance of conception and healthy, full-term pregnancy. Call us today at +918929020600 for an appointment.
In this article, we will look at: 1. What is the difference between IUI and IVF? 2. Is IUI more successful than IVF? 3. Is IUI cheaper than IVF? 4. What are the risks of multiples in IVF? 5. When should I try IUI first? 6. What are the conditions treated through IVF? The difference between IUI and IVF is actually quite broad; in fact, there are few similarities between them other than achieving pregnancy. Understanding the differences between IUI and IVF will give you an idea to begin your conversations with one of our fertility experts and help you choose the exact procedure for your treatment. Here’s what you need to know, 1. What is the difference between IUI and IVF? Couples seeking fertility treatment often prefer to start with IUI as it is seen as a less invasive procedure than IVF. The treatment involves the insertion of prepared sperms directly into the woman’s uterus close to the time of ovulation, via a thin catheter. This is typically synchronized with ovulation induction drugs, but can also be done on a natural cycle. (1) (2) On the other hand, IVF is a process which consists of several stages and requires more than one procedure. On the first stage, the ovaries are stimulated using a series of fertility medications, next the patient undergoes egg retrieval which is performed with a small incision under a mild anesthetic. After the embryos have been created and developed to a certain stage in a lab, they are placed directly into the woman’s uterus in the Embryo Transfer (ET) procedure. Moreover, an IVF treatment requires the expertise of an embryologist as well as high-technology laboratory equipment for the cultivation of embryos. The procedure gets more complex if genetic testing is required. (3) (4) 2. Is IUI more successful than IVF? Before differentiating the success rate, one must keep in mind that the success of IUI and IVF largely depends on several factors like woman’s age, the reason for infertility, doctor’s experience, and fertility drugs used. With IUI treatment, women under 35 have 10 to 15 percent chance of getting pregnant on the first cycle. (5) (8) Following are the success rates per couple according to the cause of infertility: 55.6 percent for cervical factor infertility 47.4 percent for anovulation (problems with ovulation) 41.7 percent for male factor infertility 37.6 percent for oligospermia (less than 20 million sperm per ml) 35.1 percent for unexplained infertility 13.4 percent for asthenospermia (poor sperm motility) 10.7 percent for endometriosis With IVF treatment using a woman’s own eggs, the average success rates range from 45 percent to 50 percent for patients under 35 years old, which increase with age. The success rates can go up even higher, within the 60 to 70 percent range, when the embryos are genetically tested and selected before transfer. Success rates for both procedures drop tremendously for women over 40 years, who are using their own eggs. The following are the success rate on the first cycle of IVF treatment according to women’s age: Younger than 35 years, the percentage of live births per egg retrieval is 54.4 percent. Ages 35 to 37 years, the percentage of live births per egg retrieval are 42 percent. Ages 38 to 40 years, the percentage of live births per egg retrieval are 26.6 percent. Ages 41 to 42 years, the percentage of live births per egg retrieval are 13.3 percent. Ages 43 and up years the percentage of live births per egg retrieval is 3.9 percent. 3. Is IUI cheaper than IVF? The factors of time and money are both ways when comparing IUI versus IVF. A single round of IUI is a much shorter process than a single IVF cycle, so if your first cycle is successful, it could be the quickest route to bringing home a baby. However, usually, a couple has to undergo three or four IUI cycles to achieve the same success rate that may have been achieved in a single cycle of IVF. From the perspective of cost, an IUI is typically cost 10 times less than the cost of a single IVF cycle. This is a serious consideration for many IVF patients, especially those whose insurance does not cover infertility treatment. Even though the cost of a single IUI is low, the costs can add up if multiple IUI cycles are required. Depending on your diagnosis and chances of conceiving through IUI, it may be more cost-effective to go directly to an IVF cycle rather than dealing with multiple failed IUI cycles. Unfortunately, as women age, eggs also age, and many patients find themselves in the dilemma of time versus money. Due to the gap in success rates between the IVF and IUI treatments, some patients in their late 30s to early 40s may get pregnant faster by going directly to IVF rather than having several failed IUI cycles. (6) 4. What are the risks of multiples in IVF? Multiples can cause complications for both the mother and the babies. Many women undergoing IUI are given stimulating hormones or drugs to help induce ovulation. These medications can result in the release of more than one egg in a given cycle, which increases a couple’s chances of having twins or multiples. A good doctor will carefully monitor your follicles and the eggs to make sure that only a safe number is mature before the IUI, but still, the risk is not entirely eliminated. On the other hand, with genetic screening of embryos in IVF treatments, most modern fertility clinics now transfer only one embryo per IVF cycle. Only in certain circumstances, the doctor may decide to transfer two embryos into the uterus. The remaining embryos left from an IVF cycle are frozen so that they can be used in future treatments. (7) 5. When should I try IUI first? IUI can be an ideal first line of treatment for many patients, depending on their diagnosis and circumstances. This treatment is often very effective for a patient who (9): Has at least one unblocked fallopian tube Is able to ovulate with the help of fertility medication Has a healthy ovarian reserve Has a normal uterine cavity A patient may be a good candidate for trying IUI in the following conditions: Cervical Issues: Hostile cervical mucus or scarring can prevent fertilization, and IUI provides a way to bypass these obstacles. Mild Ovulation Issues: When used with fertility medications, IUI can help women with irregular ovulation cycles conceive Donor Sperm: A patient or couple may use donor sperm with IUI to conceive. Mild Male-Factor Infertility: By preparing a concentrate of healthy and active sperms samples in a lab and placing the sperm directly into the uterus can overcome sperm motility issues or impotence. After Male Fertility Preservation: Some men choose to freeze their sperm before cancer treatment or surgery which could impact their fertility. After surgery, assuming that the female partner is a good candidate, IUI can be used to achieve pregnancy. Same Sex-Couples: Female couples may use donor sperm, and male couples may use their own sperm and a gestational surrogate. 6. What are the conditions treated through IVF? Some patients are likely to have better results by skipping IUI and beginning their fertility treatment with IVF. This is a choice each patient will have to decide for himself or herself, after consultation with their fertility specialist. IVF is a better option for patients who (10): Are over the age of 38 Have blocked fallopian tubes Have reduced ovarian reserve Decide to use donor eggs Suffer from advanced endometriosis Are dealing with severe male-factor infertility which may require the use of advanced technologies such as intracytoplasmic sperm injection (ICSI) May require genetic screening Whether you ultimately choose IUI or IVF, the first step is to contact Elawoman to find the ideal infertility doctor and clinic for your treatment. Elawoman can help you find the best doctor and clinic as per your treatment requirement. We have a vast list of reliable and verified doctors in the industry from which you can choose. Moreover, we also offer medical loans at zero percent interests. Book your free appointment now by calling us at +918929020600
Infertility treatments include various treatments such as In Vitro Fertilization (IVF), Intrauterine Insemination (IUI), Intracytoplasmic Sperm Injection (ICSI), and Testicular Epididymal Sperm Aspiration (TESA) procedures. Many infertility treatments including hormone treatments, fertility drugs, and surgery significantly improve the chances of getting pregnant. Also, assisted reproduction uses various medical techniques to fertilize an egg successfully. (1) The most common infertility treatment among all these fertility treatments is In Vitro Fertilization (IVF). This process helps in fertilization of extracted eggs with the sperm outside a human body in an advanced IVF laboratory. It is also used to treat damaged fallopian tubes, male factor infertility, ovulation disorder, and unexplained infertility. (2) Infertility treatments increase the chance of having a positive pregnancy to an infertile couple. However, to understand the cause of infertility a couple can undergo infertility evaluation. To help all the infertile couples to get the best fertility centers in Jaipur, we have come up with a list of the best fertility clinics in Jaipur with a high success rate. These centers in Jaipur provides the best infertility treatments at a reasonable cost. In this article, we will talk about the best fertility clinics in Jaipur who provides the best-required treatment to their patients. The complete information about the centers has been given below such as their location, services provided and timings. Here is the list of Best fertility centers in Jaipur: CK Birla International Fertility Centre Shekhawati IVF Center Diva IVF Centre Morpheus Mangalam International IVF Center 1. CK Birla International Fertility Centre CK Birla International Fertility Centre is one of the best IVF clinics in Jaipur. This centre provides a wide range of services related to Obstetrics, Gynecology, Orthopedics, Neonatology, Infertility, and Fetal medicine. The hospital also facilitates state-of-the-art diagnostics, IVF laboratory including a modular egg collection theatre and Andrology lab. It is famous for its well-furnished operation theatres, spacious rooms, advanced labor, and recovery rooms. CK Birla International Fertility Centre is committed to delivering magnificent quality health services to every patient. The centre comprises more than 75 beds and is expanded over an area of 78,000 square feet. The team practicing at this center treats their patients with respect, dignity, and care. The center provides various medical services round the clock such as diagnostics, radiology and pathology and Pharmacy. CK Birla International Fertility Centre keeps its patients comfort as their primary priority. Since it has started operating, the center is reputed for providing high-quality treatments to its patients. (3) The centre has been offering a comprehensive range of basic and advanced infertility treatments effortlessly to both men and women for more than a decade. The centre is visited by one of the best infertility doctors in India i.e. Dr. Renu Sharma. She has been serving the best of her services efficiently in her respective medical field for more than one and a half decades. In her decades’ experience, Dr. Renu has helped numerous families in fulfilling their parenthood dreams. The approach of supporting patients at emotional stages of fertility care maximizes the chances of having a healthy baby. She has her specialization in Assisted Reproduction. Dr. Renu has taken her extensive training in Reproductive Medicine from the International Institute of Reproduction and Fertility Training. Services: Infertility assessment, IVF, IUI, ICSI, High-risk pregnancy care, Gynecology Laparoscopy procedures Location: J - Block, Mayfield Garden, Sector 51, Gurugram, Haryana, 122018 Timings: Open 24 hours IUI package cost: Rs.15,000 IVF package cost: Rs. 1,50,000 Surrogacy package cost: Rs. 11,00,000 Website Link: https://www.internationalfertilitycentre.com/ivf-centre-jaipur Reviews of CK Birla International Fertility Centre: "I want to thank CK Birla International Fertility Centre to help us live our dream of becoming parents. My husband and I were very nervous before consulting the professionals at the centre because my case was complicated and my one IVF cycle already failed in the past. The team at this center were very supportive and understanding throughout our journey. Finally, with the grace of God and the medical staff, we are blessed with a baby girl today". - by Julie and Shikhar Dhawan Book here to get an instant FREE appointment at CK Birla International Fertility Centre. 2. Shekhawati IVF Center Shekhawati IVF Center is one of the best fertility centers in Jaipur. The centre is well equipped with modern medical technology and devices to provide every treatment with precision and care. The center offers multiple treatments related to Obstetrics and Gynecology treatments, Radiology, Orthopedics, Gastro Science, and minimal access bariatric. (4) The center includes 2 modular Operation Theatres, 1 Philips FD 10 Cath lab for serving the best treatment to its patients. This medical center has received accreditation from the National Accreditation Board for Hospitals and Healthcare Providers (NABH) and National Accreditation Board for Testing and Calibration Laboratories (NABL). The main aim of the center is to provide quality health care services which are crafted with the latest medical technology. Shekhawati IVF Center includes highly well-equipped infrastructure and serves its treatments with the help of competent and devoted professionals. Dr. Renu Jain is one of the specialized IVF doctors at the clinic who has treated many infertile couples with commendable success. The hospital also assures a high success rate for first time IVF patients. Accredited by the Indian Council of Medical Research (ICMR), this medical centre is highly reliable and affordable. (5) Dr. Renu treats her patients with care and respect, thus helping them fetch the desired results. She has gained extensive training in operating multiple advanced technologies in the healthcare sector. She understands the situation of her patients and supports them throughout their journey. Services: In Vitro Fertilization (IVF), Pregnancy-related problems care and treatment, Intrauterine Insemination (IUI), Sperm Freezing procedures Location: 2, Kedia Palace Road, Pravasi Nagar, Murlipura, Jaipur, 302039 Timings: Open 24 hours IUI package cost: Rs. 20,000 IVF package cost: Rs. 1,50,000 Website Link: http://www.shekhawatihospital.org Reviews of Shekhawati IVF Centre: "After unsuccessfully trying to conceive naturally for many years, I and my husband refused to give up on our dream and we decided to go for an IVF cycle. It was an unexpressive feeling we were shocked and happy to hear that it was a positive report. The facilities, care, and support of the staff practicing at Shekhawati IVF Center helped us to live our parenthood dream. We are thankful to all the staff members at Shekhawati IVF Center for understanding and taking care of my wife." - by Mr. and Mrs. Trivedi Book here to get an instant FREE appointment at Shekhawati IVF Centre. 3. Diva IVF Center Diva IVF Centre is one of the best IVF centers in Jaipur. The center has been offering its immense services and facilities since its inception. The services rendered by the center are In Vitro Fertilization, Intrauterine Insemination, Infertility Assessment and Treatment, Menopausal care and problems treatment, Urogynecology services, Pregnancy-related problems and care, Andrology services, Diagnostic and operative hysteroscopy procedures. Diva IVF Center is famous for its excellence in maternity, fertility and women's health. This IVF centre has received certifications from Joint Commission International (JCI), Indian Council of Medical Research (ICMR), and the prestigious National Accreditation Board for Hospitals and Healthcare Providers (NABH). (6) The center includes state of the art medical technologies to offer the best possible medical treatments to its patients. The professional staff practicing at this center helps in increasing the high success rate at a good speed. The centre has achieved a record of having the highest no. of successful pregnancies through IVF treatments and associated surgeries. The medical team at Diva IVF Centre is dedicated to their respective roles. The professionals at Diva IVF Centre put a lot of effort to achieve the common vision and larger goals of the hospital. The center is served by Dr. Shikha Gupta. She has completed her MBBS and MS in Obstetrics and Gynecology from a prestigious medical college i.e. BJ Medical College. She has been working in the field of infertility and gynecology for more than a decade now. Dr. Shikha has taken her extensive training in operating advanced technologies with modern techniques. She treats her patients with care and dedication. Dr. Shikha understands their problems and suggests the best possible treatment for positive outcomes. She has worked as an experienced tutor in a FOGSI recognized training centre for IVF and Laparoscopy procedures as a teaching faculty. She is very active and keeps herself updated by attending CME courses and short training courses. (7) Services: Infertility assessment and treatment, Pregnancy related problems and Care, IVF, and IUI procedures Location: 11-G, Olive Homes, Near Kesar Nagar Circle, Muhana Mandi Road, Mansarovar ExtensionJaipur (302018) Timings: Monday to Saturday - 8:30 am to 7:00 pm IUI package cost: Rs. 18,000 IVF package cost: Rs. 1,00,000 Website Link: http://www.divawomenclinic.com Reviews of Diva IVF Centre: "It was over six years ago when my partner and I started trying for a baby. I got pregnant naturally two times but sadly miscarried on both occasions. Then we were recommended to opt for IVF procedure. Then we started comparing the services, facilities and IVF cost of various fertility centers and we agreed to with Diva IVF Centre. We are proud that we made the right choice and are now blessed with triplets. All thanks to the medical team of Diva IVF Centre." - by Naushad and Raima Kureshi Book here to get an instant FREE appointment at Diva IVF Centre. 4. Morpheus Mangalam International IVF Center Morpheus Mangalam International IVF Center is one of the best fertility Clinics in Jaipur. The center renders a wide range of services such as In Vitro Fertilization (IVF), Intrauterine Insemination (IUI), Intracytoplasmic Sperm Injection (ICSI), and Cryopreservation techniques. This fertility center provides various world-class facilities and services related to infertility treatments with the use of state of the art medical facilities. The professional medical staff at this center serves their patients with dedication and care. It is the first and the foremost largest chain of Indo-German fertility center in India. The center is related to a team of leading gynecologists and multiple specialists in various departments in the country. Morpheus Mangalam International IVF Center is one of the successful branches of Morpheus Fertility Center. All these fertility centers are well equipped with all the latest state-of-the-art equipment across the world. The centre has registered the highest success rate to date with the help of its extraordinary medical staff who are well-trained in the medical treatments and surgeries. (8) The center renders its services at an affordable cost to its patients. It has also received multiple accreditations and certifications from various organizations well-known in the medical sector. It has provided quality medical care and has registered the highest success rates at par with international standards. The medical and paramedical staff of the clinic are internationally trained to make sure that the patients receive hassle-free healthcare services during their medical treatments. (9) Morpheus Mangalam International IVF Center is served by one of the best infertility doctors in Jaipur i.e. Dr. Anju Mathur. She has completed her MBBS and post-graduation in obstetrics and gynecology from SMS Medical College located in Jaipur. She has also pursued her Senior Residency from one of the most prestigious medical institutes of India i.e. AIIMS in New Delhi. Dr. Anju has her special expertise in gynecologic endoscopies and high-risk obstetrics cases. (10) Services: Infertility assessment,IUI, IVF, ICSI, and Cryopreservation techniques Location: C - 30 Baraf Khana, Adarsh Nagar Raja Park, Jaipur - 302004 Timings: Mon to Sat- 9.30 am to 6.30 pm IUI package cost: Rs. 20,000 IVF package cost: Rs. 1,20,000 Website Link: https://www.morpheusivf.com Reviews of Morpheus Mangalam International IVF Center: "I was suffering from endometriosis when my husband and I were trying to have our baby. We visited various centers for IVF treatment. We were nervous and excited at the same time. But the medical staff at Morpheus Mangalam International IVF Center took care of us in a positive manner. We were astonished by the facilities provided by the center and its staff. Till the day of my discharge, the doctor attended to me in each of my treatment appointments. We are thankful to the medical staff practicing at this center for their support and understanding. We are now blessed with a baby girl." - by Mr. and Mrs. Kashyap Book here to get an instant FREE appointment at Morpheus Mangalam International IVF Center. The best fertility centers in Jaipur have been serving its patients with full compassion and care for decades. IVF procedure helps all the infertile couples to fulfill their dream of parenthood successfully. Infertility procedures have taken an appreciating spot in the field of medical treatments. IVF process helps in fertilization of the egg with sperm in a modern IVF laboratory. It is one of the type of Assisted Reproductive Technology (ART). Elawoman is a healthcare firm that helps every infertile couple to get an appointment with one of the best fertility clinics in Jaipur. We help you get the best infertility treatment under the expertise of the top infertility doctors at an affordable cost. However, one can get more information related to various fertility centers and infertility doctors at elawoman.com. You can also contact our team of experts on +918929020600.
Infertility is defined as an inability to achieve a normal pregnancy after 12 months or more even after regular unprotected sexual intercourse. Infertility may result from an issue with either the male or female partner or a combination of factors that interfere with pregnancy. Fortunately, there are many safe and effective therapies that significantly improve the chances of getting pregnant. If a woman is infertile, the doctor analyses her health history, medications, sexual history, and her sexual activity. Testing starts with a medical history and physical exam, including a pelvic exam. After this, the doctor makes sure that she ovulates regularly and her ovaries release eggs. It is followed by blood tests to measure hormone levels. Ovaries and uterus may be examined by ultrasound and X-ray test in order to check uterus and fallopian tubes. (1) Causes of Infertility About 80 percent of couples suffer from infertility and it is either associated with ovulation problem, blockage of the fallopian tubes, or poor quality or count of sperms. In 5 percent to 15 percent of couples, all tests are normal, yet the cause remains unknown. Following are some of the causes behind infertility: Ovulation disorders when there are problems relating to the release of eggs from ovaries. These include hormonal disorders such as PCOS (polycystic ovary syndrome), hyperprolactinemia and thyroid problems (hyperthyroidism or hypothyroidism). (2) Uterine or cervical abnormalities (presence of polyps or fibroids in the uterus). Blocked or damaged fallopian tube which is often caused by a pelvic inflammatory disease. Endometriosis, when tissue that normally lines the inside of the uterus grows abnormally outside the uterus. Primary ovarian insufficiency or early menopause, which occurs when ovaries stop working and menstruation ends before age of 40. Pelvic adhesions are bands of scar tissue that bind organs after pelvic infection, appendicitis, or abdominal or pelvic surgery. Female fertility declines with age. In women, decrease in fertility begins around the age of 32 years. Smoking significantly boosts the risk of infertility in both men and women, and it may weaken the effects of fertility treatment. Smoking during pregnancy increases the chance of miscarriage, birth defects and pregnancy loss. Passive smoking has also been associated with lower fertility. Any amount of alcohol consumption can affect the level of fertility. Being obese or overweight can increase the risk of infertility in women as well as men. Sexually transmitted infections like Chlamydia can damage fallopian tubes in a woman and cause inflammation in a man's scrotum. Exposure to pesticides, herbicides, metals, such as lead, and solvents have been linked to fertility problems in both men and women. Mental stress can reduce sexual anxieties or desires. This can affect female ovulation as well as male sperm production. Other medical conditions associated with the absence of menstruation (amenorrhea) or delayed puberty such as poorly controlled diabetes, celiac disease and some autoimmune diseases such as lupus, can affect a woman's fertility. Treatment for Infertility In women, infertility is treated with: 1. Fertility medicines Fertility medicines are usually prescribed to women as they are mostly used to help with ovulation problems. Some of the common fertility medicines include (3): Clomifene: It boosts ovulation in women who do not ovulate regularly or who cannot ovulate at all Tamoxifen: It is an alternative to clomifene. It is also offered in case of ovulation problems. Metformin: It is prescribed for women with polycystic ovary syndrome (PCOS) Gonadotrophins: It is a popular drug to stimulate ovulation in women, and may also improve fertility in men Gonadotrophin-releasing hormone and dopamine agonists: This is also another type of medication prescribed to encourage ovulation 2. Surgical procedures Surgical procedures such as fallopian tube surgery may be required in case fallopian tubes are blocked or scarred. For cases like Endometriosis, fibroids and PCOS, laparoscopic surgery may be the best option. It is used mainly to destroy or remove fluid-filled sacs called cysts. It can also be used to remove submucosal fibroids (small growths in the womb). A minor surgical procedure called laparoscopic ovarian drilling can be used in women with PCOS. (4) 3. IUI (Intrauterine Insemination) Intrauterine Insemination (IUI) is also called Artificial Insemination. It is a fertility treatment that involves placing sperm inside a woman's uterus for fertilization. The motive of IUI is to increase the number of sperms that reach fallopian tubes and subsequently increase the chance of fertilization. (5) 4. IVF (In Vitro Fertilization) IVF is a process of fertilization where mature eggs are collected from ovaries and fertilized by sperms in a lab. After the fertilized egg (zygote) undergoes embryo culture for 2 to 6 days, it is implanted in a woman's uterus, with the intention of establishing a successful pregnancy. In Vitro Fertilization is a type of Assisted Reproductive Technology used for infertility treatment and gestational surrogacy. (6) 5. Intracytoplasmic Sperm Injection (ICSI) Intracytoplasmic sperm injection or ICSI is a process where a single sperm is injected into an egg to achieve fertilization during an IVF procedure. ICSI is useful for men with low sperm concentrations. (7) 6. GIFT (Gamete Intrafallopian Transfer) Gamete Intrafallopian Transfer (GIFT) is a process where an egg and sperm, or gametes, are not fertilized outside the body. Instead, they are placed together into one of a woman's fallopian tubes to undergo fertilization. (8) 7. ZIFT (Zygote Intrafallopian Transfer) Zygote Intrafallopian Transfer is a process where a zygote is placed in one of the fallopian tubes. This is usually done via laparoscopic surgery. (9) Tips to Increase Fertility There are a number of strategies that can increase the chances of pregnancy. Few tips to increase fertility are discussed as under (10): Quit smoking because it has multiple negative effects on fertility and general health of the mother as well as on that of the fetus. Avoid alcohol because it can impair a woman’s ability to conceive and have a healthy pregnancy. Limit caffeine intake and exercise moderately. Regular exercise is important for overall well being, but exercising so intensely that it affects periods causing them to get infrequent or go missing can affect fertility. Avoid being overweight or underweight as it can affect hormone production and cause infertility. The inability to become pregnant is very difficult to deal with and can impact every aspect of life. Infertility is a common problem today but it can be overcome with the help of treatments like IVF, IUI, ICSI and GIFT. The options that are best depend on one’s personal health condition and the cause of infertility. For the latest fertility news, tips and updates, follow Elawoman blog. Elawoman can assist you to reduce the stress associated with infertility from a medical, emotional, and financial perspective. Elawoman has helped thousands of infertility patients realize their dream of becoming parents. Our services can enhance your chance of conception and healthy, full-term pregnancy. Call us today at +918929020600 for an appointment.
Assisted reproductive technology (ART) is used to address infertility problems among both men and women. ART is mainly associated with the field of reproductive endocrinology and infertility. Some forms of ART are also used with regards to fertile couples for genetic reasons such as preimplantation genetic diagnosis. The most common complication of ART arises in the case of multiple pregnancies. However, it can be prevented or reduced by limiting the number of embryos that are put into the woman's uterus. (1) Process of ART The process of ART involves surgically removing eggs from a woman’s ovaries, combining them with sperm in the laboratory, and returning them to the woman’s uterus or donating them to another woman. Assisted reproductive technology may not include treatments in which only sperms are handled such as intrauterine or artificial insemination or procedures in which a woman takes medicine only to stimulate egg production without the motive of having eggs retrieved. The most common and effective type of ART is IVF (In vitro fertilization). ART procedures may sometimes use donor sperms and eggs or previously frozen embryos. It may also involve a gestational carrier or a surrogate. A surrogate is one who agrees to carry and give birth to a baby for another person. In case of a gestational carrier, a woman becomes pregnant with the embryos formed using sperms from the male partner or with an egg from the female partner or with both. (2) Different types of ART Some of the common methods of ART include the following: 1. IVF (In Vitro Fertilization): IVF is by far one of the most commonly used forms of ART. In Vitro Fertilization is a type of assisted reproductive technology used for treating infertility and gestational surrogacy. The process of IVF involves stimulating and monitoring a woman's ovulatory process, removing an ovum or ova (egg or eggs) from the woman's ovaries and letting sperm fertilize them in a liquid in a laboratory. After the fertilized egg undergoes embryo culture for two to six days, it is implanted in the same or another woman's uterus, with the intention of establishing a successful pregnancy. A fertilized egg may be implanted into a surrogate's uterus, where the resulting child is genetically unrelated to the surrogate mother. Some countries have banned or otherwise regulated the availability of IVF treatment, giving rise to fertility tourism. Restrictions on the availability of IVF include age and costs, in order for a woman to carry a healthy pregnancy to term. In Vitro Fertilization is generally used in cases when invasive or expensive options have failed or been determined unlikely to progress. IVF is often used in for women whose fallopian tubes are blocked. Sometimes multiple embryos may develop, which can be frozen for use in later transfer procedures. (3) 2. Gamete Intrafallopian Transfer (GIFT) GIFT was launched as a more ‘natural’ version of In Vitro Fertilization (IVF). In this method, instead of fertilization occurring in a culture dish in a laboratory, eggs are retrieved from the ovaries and inserted between two layers of sperm in fine tubing. This tubing is then fed into one of the woman’s fallopian tubes, where the egg and sperm are left to fertilize naturally. GIFT may be used as an option for couples who do not want to use IVF but avoid conception outside the body. The eggs are harvested and stimulated in a similar fashion to IVF. With the increasing success rate of In Vitro Fertilization (IVF), GIFT is rarely done nowadays. (4) 3. Intracytoplasmic Sperm Injection (ICSI) ICSI is a special form of In Vitro Fertilization technique that helps in the formation of an embryo by injecting a single sperm directly into the mature egg or ovum. ICSI is useful in the preparation of sperms and formation of embryos which are finally transferred into the uterus or fallopian tube. ICSI is often used for couples when there are serious problems with the sperms. Sometimes it may also be used for older couples or for those with failed IVF attempts. (5) 4. Artificial Insemination( IUI) Artificial insemination (AI) is also known as Intrauterine Insemination (IUI). Artificial Insemination (AI) involves the deliberate introduction of sperms into a female's cervix or uterine cavity for the purpose of achieving a pregnancy. Artificial Insemination comes under ART (Assisted Reproductive Technology) and may employ sperm donation techniques. Some of the available AI (Artificial Insemination) techniques include intracervical insemination and intrauterine insemination. The main beneficiaries of Artificial Insemination are single mothers, women who are in a lesbian relationship or women who are in a heterosexual relationship but with a male partner who is infertile. Intracervical Insemination (ICI) is one of the easiest and most common AI (Artificial Insemination) techniques that can be used at home for self-insemination without the assistance of a medical practitioner. If a pregnancy is not achieved after a few Artificial Insemination attempts, the use of IVF or ICSI may be recommended. (6) 5. Ovulation Induction (OI) Ovulation Induction (OI) is the stimulation of ovulation by medication. Ovulation Induction (OI) may be used by women who are not ovulating at all or are not ovulating regularly. Ovulation Induction involves taking a hormone medication such as a tablet or injection, which stimulates the production of follicle-stimulating hormone. This induces the development of one or more follicles. When the follicles are large enough, another hormone is administered which helps in releasing egg from the follicle. If the couple has intercourse around this time, there are more chances of conception. (7) 6. Pre-implantation genetic diagnosis A pre-implantation genetic diagnosis procedure may be conducted on embryos before implantation and sometimes even on oocytes prior to fertilization. One of the main advantages of conducting PGD is that it avoids selective pregnancy termination as the technique makes it highly likely for the baby to be free of the disease under consideration. PGD is an addition to ART procedures and requires In Vitro Fertilization to obtain oocyte or embryos for evaluation. Preimplantation genetic diagnosis (PGD) is also used to reduce the risk or avoid transmission of a chromosomal abnormality or a genetic disease. PGD can be useful for couples who have a family history of a genetic disease or chromosomal abnormality that they risk passing on to their children. It is also useful when there are repeated miscarriages or repeated IVF failure or for women over 36-38 years of age. (8) Risk of ART Some of the risks associated with ART are as follows: An increased risk for medical complications with both the mother and baby such as low birth weight, placental insufficiency, chromosomal disorders, preterm deliveries, gestational diabetes, and pre-eclampsia Risk of heterotopic pregnancy (simultaneous intrauterine and extrauterine pregnancy) Genetic disorders and preterm birth (visual impairment and cerebral palsy) Membrane damage (9) (10) Nowadays, ART may also be used in surrogacy arrangements, although not all surrogacy arrangements involve ART. This method is most suitable for people who have already gone through various infertility treatment options but who still have not achieved pregnancy. For more information on IVF and fertility treatments, you can follow Elawoman blog. If you are looking for treatments like IVF, ICSI, and IUI, Elawoman can help you in finding the best doctors according to your needs and fixing appointments. You can contact us at +918929020600.
Let’s Discuss in More Details About Sperm DNA Fragmentation: What is Sperm DNA Fragmentation? What are the Factors that Damage Sperm DNA? What are the Causes of Sperm DNA Fragmentation? Who can Benefit from Sperm Fragmentation Test? The significance of DNA Fragmentation Test? What are the Advantages of Sperm DNA Fragmentation Test? DNA fragmentation is a test for male fertility which measures the amount of damaged DNA in a given sperm sample. DNA fragmentation can occur spontaneously or it can be done intentionally by laboratory personnel. Spontaneous DNA fragmentation is fragmentation that gradually accumulates in a cell. DNA fragmentation is more common among men with sperm motility defects. It is useful for predicting outcomes for In vitro Fertilization (IVF) and its expansion intracytoplasmic sperm injection (ICSI). The main units of measurement are the DFI (DNA Fragmentation Index). The abnormal genetic material present in the sperm, can, in turn, lead to male subfertility, IVF failure, and miscarriage. A conventional semen analysis is done to check the sperm concentration while motility analysis and morphology assessment cannot analyze the sperm at the molecular level hence DNA fragmentation test helps in finding out faulty DNA in sperms. Sperms with high DNA fragmentation fertilizing younger oocytes carry a better prognosis of achieving a successful pregnancy. All men have some amount of damaged DNA in their sperms; higher damage may indicate greater difficulty in achieving pregnancy with IVF and IUI. (1) (2) Factors that Damage Sperm DNA DNA damage increases with age, men in their 50s or 60s have a higher percentage of sperm fragmentation as compared to men in their 30s or 20s. (3) Other factors that damage sperm DNA include the following: Exposure to various chemicals or toxic agents Excessive heat Chronic infections in the prostate Chemotherapy Radiation or smoking In order to prevent further damage to DNA, doctors may recommend drawing sperms directly from the testicle with a needle or suggest some antioxidant vitamins that help minimize the damage. Causes of Sperm DNA Fragmentation One of the major contributing factors for sperm DNA fragmentation is oxidative stress, which can be associated with one or more of the following (4): Intrinsic causes such as deficiencies in recombination during Spermatogenesis Abnormal Spermatid Maturation Infection and Pyrexia Variations In Sperm Protamine Expression Abortive Apoptosis Elevated Testicular Temperature Recreational drugs Extrinsic causes like Lapse of Time from the Ejaculation Excessive Smoking and Alcoholism Oxidative Stress and Unhealthy Diet Environmental and Occupational Pollutants Advanced Chronological Age (5) Who can Benefit from Sperm Fragmentation Test The need for Sperm Fragmentation Test arises when there is (5): Unexplained infertility Arrested embryo development Poor blastocyst development Unsuccessful attempts for IVF and ICSI treatments Miscarriage Advanced chronological age Varicocoele Poor semen parameters Exposure to harmful substances The significance of DNA Fragmentation Test The fragmentation test can determine what percentage of sperms has fragmentation. Less than 15 percent damage means a very good outcome, while 16 to 29 percent means a moderate outcome. More than 30 percent damage means higher sperm fragmentation that indicates difficulty in achieving a healthy pregnancy, even with IVF. High sperm DNA fragmentation level affects blastocyst development and there are higher chances of failed assisted conception treatment and miscarriage. (6) Sperm DNA fragmentation is higher in subfertile men with abnormal sperm parameters; however, men with normal sperm parameters can also develop sperm abnormality. Embryos from sperm with highly fragmented DNA are likely to have a poor prognosis. High level of DNA fragmentation could result in the initiation of natural cellular death (apoptosis) and abnormalities in the offspring. Different kinds of Test for Sperm DNA Fragmentation There are different types of tests available to assess the percentage of sperms with DNA fragmentation, such as the SCSA, TUNNEL assay and COMET assay. However, the test that has received the most attention is the Sperm Chromatin Structure Analysis (SCSA). (7) Sperm Chromatin Structure Analysis (SCSA) During the SCSA test, a special dye is allowed to enter into the sperm cell, and the sperm is treated with a chemical. Generally, sperms with fragmented DNA take up more of the dye once it makes its way into crevices in the DNA molecule. With the help of a procedure called flow cytometry, the sperm that takes up lots of dye can be easily be differentiated from the sperm that takes up only a little dye (sperm with normal DNA). Finally, the percentage of each sperm with fragmented DNA can be graphed by using a computer program. A patient with a result of 8.2 percent comes under excellent to a good category with 8.2 percent of the sperm cells containing DNA damage. The SCSA test recommends that patients with higher than 25percent should skip IUI and go straight to IVF/ICSI for better results. (8) Sperm Comet Test Sperm Comet test is a second-generation DNA test that provides unique information by measuring the amount of DNA damage in individual sperm. Sperm Comet results predict the success of infertility treatments and the treatment type most likely to succeed. The percentage of sperm with DNA damage is detected with this test. If the result shows 45 percent damage, shows an average of 45 percent DNA damage in each sperm that was assessed. A flow cytometer is used for monitoring a fluorescent probe that interacts with the DNA molecule. (9) Advantages of Sperm DNA Fragmentation Test Sperm DNA fragmentation test provides a reliable analysis of sperm DNA integrity that may help to identify men who are at risk of infertility. It also provides information for clinical diagnosis, management, and treatment of male fertility. Treatment of High Sperm DNA Fragmentation Treatment of High Sperm DNA Fragmentation depends essentially on its causes. If the DNA damage is due to free radicals, lifestyle changes and a healthy diet designed to protect oxidative stress may help reduce the levels of DNA fragmentation. (10) Other treatment options include the following: Antibiotics in the co-existence of an infection Changes in lifestyle factors known to cause DNA damage such as taking drugs, smoking in both partners, tobacco and occupation Maintaining a healthy diet like eating foods rich in antioxidants, vitamin C & E, eating green vegetables, drinking lots of water, Varicocele surgery Testicular aspiration of sperm may have better DNA integrity than ejaculated sperm since DNA damage occurs at the post-testicular level ICSI Treatment rather than IVF Treatment Antioxidants for three to six months such as astaxanthin either alone or combined with other antioxidants are also known to reduce DNA damage. Initiatives can be taken by going through a second test three months later to reduce the levels of DNA fragmentation. Doctors may recommend a patient with high level of fragmented DNA to go for ICSI treatment rather than starting with IVF directly. This significantly reduces the length of treatment time and improves the chances of success. If you would like to find out more about male infertility assessments, you can consult Ela. Elawoman also provides medical loans at zero percent interest rate for those who need financial help. You can reach us at +918929020600.
Let’s Discuss in More Details About How Can Couples Be Benefited From Laser Assisted Hatching: What is Laser-Assisted Hatching? What is the Procedure of Laser Assisted Hatching? When Laser Assisted Hatching is Recommended? What are the Advantages of Laser Assisted Hatching? What are the Risks Associated with Assisted Hatching? What is the Success Rate of Laser Assisted Hatching? What is the Treatment Cost for Laser-Assisted Hatching? What is Laser-Assisted Hatching? Advancement in science and technology has sorted the lives of people to a great extent. Technology has been helping us at every segment from work to be done to the production of goods and even in reproduction also. Laser-assisted hatching is one of the technological advancements, which has been around us for a long time. It can be considered as one of the technological gifts for women older in age. (1) Laser Assisted Hatching is a technique used in In-Vitro Fertilization. This technique helps to improve the implantation of embryos into a woman’s uterine lining. The process creates an opening into the patient’s uterine lining allowing the embryonic cells to hatch. It is a safe technique, which helps to weaken, and thinning a small section of the zona pellucida. If the zona pellucida is harder, the case becomes more complicated. This happens because the eggs will not hatch or may use excessive energy for getting out. This can end up with repugnance to the woman’s uterus and reduces the likelihood of implantation. Reasons accompanying the same include the age of the patient because women above 37 years generally produce eggs with a harder or thicker zona pellucida as compared to younger women, another reason supporting the reduction of implantation in women with a high level of Follicle-Stimulating Hormone (FSH). (2) Procedure of Laser Assisted Hatching This procedure is performed in lab. Here the laser beam is used to hatch the outer shell to facilitate the embryo implantation. For this purpose circle of the colored beam of light is fixed. This circle locates the point where the laser will fire. This laser beam is invisible; we can only see its effects. Laser beam releases energy in the embryo shell and dissolves it. The laser is pulsed three times to create a complete gap in the shell. However, this exact technique may vary based on the power settings, technique and spot size. For a successful pregnancy, this hatching is performed without affecting the embryo. (3) When Laser Assisted Hatching is Recommended Laser-Assisted Hatching is recommended in the following cases: Patients who are more than 37 years old. (4) Patients having Frozen Embryo Replacement (FER) Patients who have faced a failed IVF or ICSI treatment Those who are going for IVF/ ICSI for the first time. They are considered poor responders because they have required a high dose of Gonadotrophins. It is a kind of infertility drug for a poor ovarian response. Those with poor quality and quantity of embryos Those who have had a low fertilization rate in earlier IVF cycle Couples going for IVF treatment with embryos that have a thick outer shell called as zona pellucida Advantages of Laser Assisted Hatching Laser-Assisted Hatching with IVF has many benefits like: In this treatment, only fewer embryos are required to be transferred Assisted Hatching can Increase the implantation success rates It allows for blastocyst culture Reduces the chance for multiple pregnancies (5) Other Assisted Hatching Methods Assisted hatching is not always assumed to make a small break or tear in the egg. There are other methods too that are practiced by different labs, accordingly. Some of the methods are mentioned as follows: Mechanical Hatching: There is a risk of controlling the size of the opening (zona pellucida) with this technique. As an embryologist keeps the embryo steady with the help of a pipette while puncturing the zona pellucida using a micro-needle. (Imagining a very thin line alongside the embryo). Mechanical Expansion of the Shell: Through this technique, hydrostatic pressure is introduced just under the shell, making it expand. This method’s idea comes from the natural expansion of the outer shell during the hatching process. Chemical Hatching: A chemical known as Tyrode’s acid is used in this treatment while treating the patient. A small amount of Tyrode’s acid is applied to the zona pellucida until the shell is breached. There is a risk of chemical exposure of the embryo under this treatment. Drilling: In this technique, vibrations are created for a conical opening. This technique uses another technology called Piezo technology. (6) Of all the methods mentioned above, chemical hatching is one of the commonly used techniques, as not every embryology lab is equipped with Laser Assisted Hatching process. Risks Associated with Assisted Hatching There are multiple risks with laser-assisted hatching. They are: Manipulation or interference with an embryo can lethally damage it, which ironically means that embryo’s natural capacity is challenged and will somehow result in non-pregnancy of the woman. (7) Another risk of assisted hatching is twinning, specifically monozygotic twins. It is an identical twin, which comes from an egg and a sperm. During the IVF treatment, chances of twinning are already increased, and researchers have found that assisted hatching may further increase the risk. However, all multiple pregnancies carry risk, but monozygotic twin pregnancies come with some more and can be dangerous for both the mother and the baby. Assisted laser hatching can cause complications for the female partner. These complications include nausea, vomiting, swelling of the face, water retention, and headache. However, these problems are not that big and can be diagnosed with simple medication. Success Rate of Laser Assisted Hatching One of the foremost questions is asking about the success rate. The success rate, in this case, is how many couples have come along with a baby in their hand after the treatment. The success rate of IVF along with laser-assisted hatching increases by up to 50 %. A Cochrane review considering a collection of 31 studies have found hatching process has improved the clinical pregnancy rates. However, the same lack of live birth rates. Ultimately, the results matter and here the live birth rates. The goal for any fertility treatment is taking a baby home, not just getting a positive pregnancy test. Embryologist’s experience plays a bigger part in making the process successful. (8) Factors that Affect Laser-Assisted Hatching Success Rate There are some factors, which can influence the success rate of Laser Assisted Hatching: Experience of the embryologist Expertise deployed during the procedure The nature of the embryo basically the thickness of the shell Quality of the infertility Centre Treatment Cost for Laser Assisted Hatching Cost of the treatment depends on many factors. Various clinics offering IVF treatment along with Laser-assisted Technique include the cost of both the treatments. It is affordable treatment in India as compared to other countries. It ranges from Rs. 20,000 to 30,000 only. Many factors that affect the cost of the treatment are mentioned as follows (9) (10): Type of infertility center City selected Experience of the Embryologist Type of treatment. For example after IVF or ICSI Number of embryos used Hope this article gave you all the information about Laser Assisted Hatching and how is it beneficial for couples. Follow elawoman.com to get all the latest updates regarding any infertility treatment, IVF, IUI, and Surrogacy. You can also call on the given number to book an appointment +918929020600.
Let’s Discuss in More Details About ZIFT: What is ZIFT? Why opt for ZIFT? Process of ZIFT as Compared to IVF? Advantages and Disadvantages of ZIFT Process? Effectiveness of ZIFT? Why is ZIFT a Better Choice? Cost of ZIFT Procedure? Each couple imagines conceiving their baby in the natural and sound way. However, in today’s unhealthy lifestyle, infertility has become a major issue. Wrong eating habits, stressful work schedules, irregular eating habits, and many such unhealthy ways prompt high odds of infertility issues. With continually evolving science and research, ZIFT or Zygote IntraFallopian Transfer is another addition to ART (Assisted Reproductive Technology) that doctors are recommending widely for infertile couples to get a baby. (1) Why opt for ZIFT? ZIFT is a choice for couples if they have tried different medicines and all have proved to be unsuccessful in leading to pregnancy. For this process, there should be at least one open fallopian tube. (2) ZIFT can likewise help considering you have the following conditions: Unexplained infertility Ovulation issues Your accomplice has a low sperm check If the sperm-check is low in the male partner, or if there were preparation issues in past IVF cycles, ZIFT can be utilized in combination with Intracytoplasmic Sperm Injection (ICSI). ICSI is a strategy that lifts the shot of treatment by infusing a solitary sperm specifically into an egg. The process of ZIFT as Compared to IVF ZIFT is a modified version of In Vitro Fertilization (IVF). ZIFT process takes place four to six weeks to complete one treatment cycle. This treatment is performed when a blockage in the fallopian tube prevents the normal binding of sperm to the egg. (3) In this process, first, ovaries are stimulated with the help of medicines. This is done to increase the chances of producing multiple eggs. After that, the produced eggs are collected through an aspiration procedure. These collected eggs are fertilized in a laboratory. Now the fertilized eggs are transferred, versus 3-5 days as used in a regular IVF cycle. The fertilized eggs are then transferred to fallopian tube within 24 hours through a laparoscopic procedure. It is done through a catheter placed deep in the fallopian tube. In the final step is to notice the early pregnancy symptoms. The doctor will use blood to confirm if pregnancy has occurred. Advantages and Disadvantages of ZIFT Process There are always pros and cons both associated with anything. If there are advantages of ZIFT then there are also some risks of this procedure. Therefore, here we are giving a brief of the pros and cons of ZIFT. (4) Advantages of ZIFT: Those couples who have extreme infertility issues can think about this strategy as help to have their baby. (5) The best thing about this technique is that the specialist can affirm the treatment of egg before inserting it in the Fallopian tube. In this way, the specialist will just choose the best and splendidly created zygote. This strategy functions admirably on those couples who have attempted no less than one year to conceive normally and have 5 to 6 fizzled cycles of IUI (Intrauterine Insemination). Disadvantages of ZIFT: There are certain disadvantages or risks associated with this strategy and accordingly not all couples settle on ART or, to be precise, ZIFT. (6) In this technique, different zygotes are embedded in the fallopian tube to build the odds of accomplishment, yet it can likewise come about into multiple pregnancies. (7) Along these lines, the chances of having twins and triplets increases. Occasionally, different pregnancies can be hazardous and there are more odds of an unnatural birth cycle. There is a danger of having an ectopic pregnancy, where the hatchling will create outside the womb in the fallopian tube itself. In such cases, it becomes necessary to expel the zygote through surgery or even the fallopian tube as well. A few women may grow excessively numerous eggs because of the fruitfulness of drugs. This can cause a few hormonal changes in the body, which are hard to deal with. A few examinations additionally guarantee that infants conceived through this treatment can have birth imperfections or disorders. Effectiveness of ZIFT The achievement rate for ZIFT differs drastically. It highly depends on a couple's fertility issue and age. Women that are more youthful have more advantageous eggs and higher achievement rates. Ladies have around a twenty-two percent possibility of conveying an infant with each ZIFT cycle. (8) Similarities and Dissimilarities Between ZIFT and IVF ZIFT and IVF both have a tendency to be ideal medications for women who have more serious infertility issues, for example, harmed fallopian tubes. ZIFT and IVF both include incipient organism culture. ZIFT and IVF both furnish the doctor with the chance to choose the best quality embryo for transfer. ZIFT transfers the treated fertilized egg is put into the fallopian tube while in IVF; the prepared embryo is transferred into the uterus. The ZIFT system varies from IVF in a way that it requires an additional surgical method called laparoscopy to transfer the embryo in the fallopian tube. Why is ZIFT a Better Choice? ZIFT (Zygote Intrafallopian transfer) is a superior choice of other infertility treatment methods. Here the developed Zygote is transferred in the fallopian tube and not in a petri dish or uterus. The pregnancy rates with ZIFT have dependably been higher than with In Vitro Fertilization-Embryo Transfer (IVF-ET) and there are numerous purposes behind this. (9) The fallopian tube gives a superior domain to the embryo when contrasted with an incubator. There is better synchronization between the embryo and uterus in a ZIFT, because of which implantation rates are superior as compared with customary IVF treatment. ZIFT enables the specialist to sidestep the cervix. This can be exceptionally useful in women with cervical stenosis, or the individuals who have experienced failed IVF treatment in the past. It is so because the embryo exchange is actually troublesome or inappropriate. Cost of ZIFT Procedure ZIFT is an expensive procedure. It typically costs from $15,000 to $ 20,000 a cycle. The cost depends upon your location, the number of medicines taken, and the number of cycles you undergo. ZIFT may cost more than traditional In Vitro Fertilization. Before going for such treatments, make sure that you are with the best specialist because ultimately the success of the treatment is all that matters. Also, be prepared that your budget allows you to go for this treatment. (10) Make sure you set aside the opportunity to completely examine the consequences of fertility tests and the diverse medicines for infertility with your specialist before settling on any choices about what will be best for you. This will help in making the correct decisions and increasing the chances of effective conceiving. I hope the article helped you with getting all the information related to Zygote Intrafallopian Transfer (ZIFT) along with the pros and cons of the same. Follow Elawoman blog to get all the latest updates regarding infertility treatments, IVF, IUI, and Surrogacy. You can also call on the given number for any ART-related query or to book an appointment- +918929020600.
In modern times, advanced medical procedures have taken a significant place in treating the medical conditions of patients irrespective of their healthcare issue. Infertility is one of the prime issues for couples who are unable to conceive naturally. Along with treatments created for curing infertility issues, various other medical procedures are introduced which are combined with the chosen treatments to receive the desired results for the patients. In the recent years, the demand for cryopreservation procedure has significantly increased due to increased support of the infertility experts along with government funding which has motivated more number of individuals to go for the embryo freezing procedure. You will be surprised to know that embryo freezing increases the chances of reproduction until 70% when compared to cases which go for natural conception or conventional IVF procedure. This proves to be useful for couples struggling hard to have babies. In countries like Europe, NHS supports In Vitro Fertilization (IVF) cycles of couples to a great extent and helps them receive up to three cycles at affordable and reasonable costs. Europe and North America have recorded the highest growth in the use of IVF treatment, which has proved to be very significant for patients. The usage of eggs, sperms, and embryo freezing in the infertility treatments have also reached to the next level in these continents. In the countries of Asia Pacific, the implementation of infertility treatments has increased significantly because of the fertility tourism and rise in the awareness related to the treatment. In this article, you will find information about different aspects of embryo preservation procedure and its contribution to the success of the IVF procedure. (1) Embryo Freezing or Embryo Cryopreservation procedure: Embryo freezing procedure is a medical technique in which embryo formed in the IVF laboratory is stored at a certain temperature. The best temperature at which infertility experts recommend storage of embryo in this technique is around -196 degrees Celsius. This temperature is proven as the most suitable one for preserving embryo in the medical laboratory in the embryo bank or fertility clinic. As per the National Embryo Donation Academy, around 5 lakhs of embryos were stored in embryo cryopreservation procedure in the United States alone. Also, the procedure of embryo cryopreservation is performed within one to six days of the formation of the quality embryo. (2) History of Embryo Freezing: Embryo Freezing first came into notice when the first baby was born in the year 1984. The baby born with the assistance of frozen embryo was named Zoe. The scientists of Monash University mentioned that the news of the baby's birth was hidden for 2 weeks to provide desired protection to the baby's family. Professor John Leeton was a significant part of the procedure of In Vitro Fertilization, which helped in the birth of the baby. As per the reports of IVF doctors, it was found that egg and sperm of the couple were fertilized in the medical laboratory. The embryo, which was thus formed, was preserved for a time period of 2 months before progressing with the transfer of the embryo into the uterus of the woman. Fortunately, the embryo got implanted with success. The woman got pregnant and the entire team leading the procedure was happy with the accomplishment. (3) (4) When is Embryo Freezing procedure recommended? There are certain specific and crucial conditions in which procedures such as embryo infertility experts recommend the freezing technique. Embryo freezing procedure is advised to patients in the following cases: Intentional delay of conception: In recent years, the number of individuals is heading towards a life where professional priorities are considered before building a family. Here, a couple or even a single individual choosing a donor egg or sperm has decided to start a family after a couple of years. In such cases, the embryo-freezing procedure is chosen for the couple. It helps them to store embryo or embryos in the right conditions. As per the recent researches published in the news publications, it is found that Total Fertility Rate (TFR) is decreasing at a constant rate. This has occurred due to the rise in the scenario of delayed marriages and late planning of babies. (1) Major health conditions: There are various health conditions, which take a toll on the fertility levels of the body. This makes an individual or couple thinks about safeguarding their eggs, sperms, or embryos for future use to start a family without facing many obstacles in their path towards parenthood. If a couple plans to have a baby, then they can simply take the assistance of the embryos stored in the medical laboratory. Some such health conditions include cancer, which needs to be dealt in a positive manner. Here, embryo cryopreservation will help individuals and couples have babies in the later years of their life as well. Will to donate embryo: Most of the couples that go for the embryo freezing procedure are often left with quality embryos. These embryos can be utilized for In Vitro Fertilization treatment of couples who are unable to conceive due to poor quality of embryos formed with their respective sperms or eggs. If a couple has chosen embryo cryopreservation procedure, then they can help other couples going for the embryo donation. Another couple can quickly pick up the embryo donation procedure, thus improving chances of success in the IVF procedure with a positive pregnancy. (5) How to prepare for Embryo Freezing/ Embryo Cryopreservation procedure? Patients need to understand that embryo-freezing procedure requires some specific preparation to make sure that the procedure ultimately leads to a successful pregnancy for the couple opting for it. Choosing for the best and proven tips will help couples in preparing for the embryo freezing procedure and receiving the desired results. Blood tests are important for screening purpose. This helps in finding out the actual health status of the patients. Ovarian reserve testing is performed to find out the quality and number of eggs. Follicle stimulating hormone (FSH) and estradiol are tested to find out egg quality and number in the concerned women. Infectious disease screening is also performed to know whether the woman is affected with HIV, Hepatitis B, and C. This prevents the passage of these serious healthcare conditions into the baby who will be born with the help of the IVF procedure along with frozen embryos. These tests are common for sperm, eggs, and embryo freezing procedures as well. Before starting with the procedure, couples need to make sure that they go for all the recommended medical tests as suggested by the infertility experts. Time to time monitoring is done under the guidance of the infertility specialists to make sure that the embryo cryopreservation procedure takes place in the right manner. (6) Methods of Embryo Freezing procedure: Embryo freezing procedure comprises of different methods, which are utilized as per the requirement of the infertility case of the patients. The most crucial and commonly used embryo freezing procedure includes Slow Programmable Freezing (SPF) popularly known as Slow Freezing along with Vitrification procedure. Each of these methods has its own set of pros and cons which are considered while choosing for the concerned procedure. 1. Slow Programmable Freezing (SPF): Slow Programmable Freezing (SPF) is one of the top methods, which assist in fertility preservation from several years now. This procedure was utilized for the first time in the year 1986. This procedure was the only reliable way to freeze eggs for nearly 2 decades until procedures like vitrification were introduced. Here, a cryoprotective agent is used to preserve the embryo for a considerable period of time as recommended by the infertility expert himself. The targeted embryo is stored at a temperature of -196 degrees to prevent any kind of damage throughout the time period of embryo cryopreservation procedure. The natural biological processes are shut down naturally in this procedure. Proper care is taken with respect to the cells, as around 30% of the cells in the embryos cannot successfully complete the insemination process, which can also tolerate the thawing procedure. The success rates of the slow freezing or slow programmable freezing (SPF) technique are a considerable one. The slow freezing procedure is possible only in the pronuclear stages. This stage of embryo development is popularly known as PN stage. Therefore, if this procedure is used, then inseminated egg cells are taken for successful completion of the same. This is because the inseminated cells have a different level of sensitivity than the non-sensitive types of cells present in the embryo. The time period, which is involved in the slow programmable freezing procedure, is around hours. This procedure is very less utilized these days. This is because of the increased time consumption. (7) 2. Vitrification: The procedure of vitrification involves various steps where the specialist utilizes a very high freezing rate when considered on per minute basis. This helps in getting the embryos frozen at a very quick rate. One of the major differences of slow programmable freezing and vitrification is that the later procedure is a modern one and the success rates of vitrification are much higher than the slow freezing procedure. These days, infertility experts highly favor the utilization of vitrification procedure with the help of which embryo freezing can occur quickly without mere wastage of time and energy. Advantages: One of the biggest advantages of vitrification is that it takes much less time to complete the procedure. It is a very rapid medical procedure, which saves a lot of time of the infertility experts and patients as well. Patients need not invest a lot of energy and can stay comfortable with the practice of the vitrification procedure. Here, infertility experts will offer time-to-time guidance and execution of this advanced medical procedure as well. The success rates of vitrification procedure are much more than that of slow programmable freezing technique. The success rate of vitrification is 91% when compared to the slow freezing technique, which is, rises till 61%. It is clearly visible that vitrification works better than a slow programmable freezing procedure. Disadvantages: The prime disadvantage of vitrification is that a very high amount of cryoprotectants is utilized in the procedure of vitrification. The cryoprotectants utilized in the procedure are known to result in cytotoxic effects on embryo. In the procedure of vitrification, cells present in the embryo come in direct contact with the liquid nitrogen used in the procedure as well. This can have a negative effect on the overall status of the cells present in the formed embryo. This can also impact on the life of the embryo, which is aimed to be stored in the medical laboratory. (8) Vitrification is much more favored type of embryo freezing technique these days than slow programmable freezing due to its advantages over the later procedure. Even infertility specialists recommend vitrification to boost success rates of the infertility procedures of couples. Storage Period of Embryos: Couples or individuals opting for embryo preservation or cryopreservation procedure need to understand that embryos can be stored for a time period of an average of 10 years. However, this can vary as per the requirement of the couple along with the regulations created in the respective country. You need to understand that some of the countries across the world have set specific regulations about the time frame within which the embryo can be preserved efficiently without affecting its quality. Individuals or couples need to discuss with their infertility expert before going ahead with the cryopreservation procedure. Most of the fertility centres offer different options for the storage of the embryos in terms of the timing of the cryopreservation. (9) Embryo Freezing procedure in IVF Centres: Embryo freezing procedure is performed in the IVF laboratory or embryology labs in a fertility center. Some of the best IVF centres across the world offer the top quality embryo freezing services which prove to be beneficial for the couples who are planning for a baby. IVF centres which offer quality healthcare services related to dealing with infertility concerns of couples ensure that couples receive desired success rates with respect to their IVF procedure. This includes storage in the form of frozen embryos and donation to couples. It is also utilized in the medical studies conducted to find out relevant information about human embryos. In cases of any of the types of donation, a proper legal agreement is signed to keep transparency and clarity about the future use of respective embryos. The embryo freezing procedure is performed under the guidance of the infertility experts and embryologists who are specialized in the field of infertility medicine. (10) Control of patients on Stored Embryos: The control of patients on embryos, which are stored with the help of embryo cryopreservation, depends on the laws and regulations which revolve around the embryo freezing procedure. You need to provide your informed consent depending on your agreeability on the specified terms and conditions. Some of the crucial aspects about which you need to know the include time duration of the storage of embryos and what would happen if you or your partner has an untimely death. You also need to get clarified that what would happen if you decide not to use those stored embryos and think about embryo donation. Before you go for the embryo cryopreservation procedure, you need to understand if your case requires any further advanced treatments to stay prepared for the future planning of a baby. You will be able to find this out after consulting infertility specialist who is experienced in performing IVF procedure with the help of embryo preservation technique. (11) Side Effects of Embryo Cryopreservation procedure: There are certain side effects of embryo preservation, which need to be understood for the proper execution of the treatment. Here are some of the side effects of embryo cryopreservation, which are quite prominently found among patients as well. Bloating or cramping: This is one of the most commonly occurring side effects, which can be seen in patients who have opted for embryo cryopreservation procedure. Vaginal Discharge: Vaginal discharge increases in women during embryo preservation procedure. In the case of a severe increase in vaginal discharge, patients need to make sure that they consult an experienced infertility expert without any kind of delay to receive proper medical advice and treatment. Overstimulation of ovaries: It is often seen that the ovaries get overstimulated during the procedure. Although, this varies from one woman to another depending on the health status of the patient. Bleeding: Many of the women also suffer from bleeding issues, which need to be dealt in the right manner to prevent further deterioration of the condition. Feeling full: Patients usually feel like they are completely full which at times creates an imbalance in their body. This can be treated under the guidance of the infertility expert. Infection: Due to several reasons, infections can be prominently seen in patients who are undergoing the embryo-freezing procedure. Most of the patients suffer from one or more types of side effects associated with embryo freezing procedure, which needs to be tackled in a smart way. An experienced infertility specialist will help couples to a great extent in planning for the embryo freezing procedure. (12) Embryo Thawing Procedure: Embryo thawing is a vital procedure in which the embryos stored at a very low temperature are warmed. This assists the stored embryos to reach a stage where they can be utilized in the infertility treatments such as In Vitro Fertilization (IVF) procedure. This helps in transferring embryo in the desired form, which leads to successful implantation in the uterus. The concerned medical specialist makes sure that the embryos formed are warmed at the predetermined temperature, which prepares the embryo for the embryo implantation procedure. (13) (14) Embryo thawing procedure timing is directly proportional to endometrial receptivity. The thickness of the uterine lining determines the success of the embryo implantation procedure. Prior to the start of the IVF procedure, certain tests are performed for efficient results to make sure that the implantation occurs successfully in the respective patient. Also, the infertility specialist recommends taking certain measures before starting with the IVF treatment. This primarily includes improving diet and lifestyle, which significantly contributes to the improvement of the lining of the uterus. So, you can understand that embryo-thawing procedure is crucial in determining the success of embryo cryopreservation or embryo freezing procedure. (13) (14) Survival rate post-thawing step: The post-thawing survival rate is a very important factor in determining the ultimate success of embryo cryopreservation procedure. Patients need to understand that there are several factors, which determine the success rate of embryo freezing procedure. One of the important results of researches was that the post-thawing survival rate was significantly higher in vitrification procedure than that of slow programmable freezing procedure. The vitrified blastocyst success rate was also higher to a certain extent than that the ones who were preserved with the slow freezing procedure. The high survival rate of embryos in vitrification will result in the reduced usage of the embryo thawing procedure for the respective embryos. Based on the expertise of the infertility specialist and case of the patient, it is important to understand that the usage of either vitrification or slow programmable freezing procedure will provide the best results to the patients. One of the studies has also concluded that the babies born with vitrification type of embryo freezing procedure are healthier than those born with a slow freezing procedure. This must be taken into priority while deciding the type of embryo freezing technique. (15) Fresh vs Frozen Embryo IVF Transfer procedure: The success rates of fresh and frozen embryo IVF transfer procedure vary based on the complications of the respective procedure. The success rates of fresh and frozen embryo transfer in IVF procedure is a controversial topic as some of the infertility experts favor fresh embryo transfer, while in some cases frozen embryo transfer is a favored one. Fresh embryo IVF transfer procedure requires the use of embryos, which are formed a few days back. This procedure does not require any kind of embryo freezing procedure utilization for achieving a successful pregnancy. Frozen embryo transfer in the IVF treatment includes the usage of frozen embryos. Some of the advantages of frozen embryo IVF transfer procedure include increased pregnancy rates and reduced miscarriage rates. Also, when frozen embryo transfer is chosen in IVF procedure, then there is a lower risk of pre-term labor, increased live births, and healthier babies are born at the end of the pregnancy, which occurred with the IVF procedure. (16) Thus, embryo freezing or cryopreservation procedure is a very useful and in-demand medical procedure in the field of infertility treatments. Now, it is known to increase success rates of the infertility treatments such as IVF procedure. Such procedures prove to be a blessing for patients who have crossed their reproductive age where they could have conceived naturally. Infertility experts motivate patients to progress with these advanced medical procedures to achieve the best possible success rates.
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