Book an Appointment
+91-7899912611
fertility treatments

World’s first Test Tube Baby - The Story Behind It

  • 4.8 (6 Votes)
  • 86283 views

The world welcomed its first test tube baby Louise Joy Brown who was conceived via In-Vitro Fertilization in the year 1978 in England. Her fathers sperm was fertilized with the egg from her mother in a laboratory and embryo thus formed was implanted into the uterus of her mother named Lesley Brown.

Lesley Brown was the mother to undergo a successful In-Vitro Fertilization and give the world its first test tube baby.  Louise Joy Brown was born in District General Hospital in Oldham, England. It was the experimental IVF process by British gynecologist Patrick Steptoe and scientist Robert Edwards that went on to become a success eventually with the birth of Louise.

Medical debate that followed

The IVF process that led to the conception of Louise Brown had become the reason of medical debate. There are ethnic groups who do not agree with the idea of this scientific advancement in the field of ART as according to them it is something unethical and an attempt to play god. After Louise Brown, there are millions of babies who took successful birth through IVF and the technology keeps on making advancement with new techniques like TESA, MESA, Sperm/ Egg/ Embryo freezing being introduced to enhance its success. Here is the complete story about the evident history:

How it all started

In the midnight, with the cesarean process, the world’s first IVF baby weighing 5 pounds and 12 ounces was delivered. Before all this began, Lesley Brown, the mother, suffered years of infertility problem and blockage in the fallopian tube was the main cause behind it. In the month of November in the year 1977, Lesley underwent the experimental IVF process. The process involved a mature egg from one of the ovaries combined with husband’s sperm to form an embryo. The combination in the laboratory dish was implanted into Lesley uterus a few days later.

first ivf baby

The famous scientist Robert Edward in collaboration with doctor Patrick Steptoe ran a long research on various fertility methods such as artificial insemination and IVF before coming up with the process plan. They both had to face a lot of hurdles and answer multiple questions after the process was formally introduced and put into use in the case of Louise. Lesley’s pregnancy found its place in headlines in almost every newspaper and was much talked about not only in the country but also across the entire world.  

Lesley and Peter Brown had their second child, a daughter, via IVF called Natalie. She went on to be the first IVF baby who conceived naturally in the later stage of life and gave birth a normal healthy child. She gave birth in May 1999. This led to the change of mind of many people that believed that an IVF baby couldn’t conceive or give birth to a normal child or even have a normal pregnancy.

After her sister, the world’s first test-tube baby, Louise Brown gave birth to a baby boy in December 2006. Louise Brown’s son, Cameron John Mullinder took a natural birth and was conceived naturally. The greatest examples of babies of first test tube baby, Louise, and her daughter left the world to believe in the experimental miracle.

Louise and her sister’s upbringing was normal despite being a test-tube baby or IVF procedure children. Louis knew her own story of being an IVF baby through the media interview of her parents. And her home life with her parents and younger sister was normal without any hurdles.Louise Joy Brown continues to live a happy married life with her two children that were born naturally. Her parents Mr. And Mrs. Brown are not anymore. Her father died in the year 2007 while her mother Lesley Brown died on 6th June 2012 in Bristol Royal Infirmary.

Revolution Caused by the IVF Thereafter

Successful birth of Louise Brown achieved by Robert Edward and Dr. Patrick Steptoe set an example and hopes to all those couples looking forward to parenthood with the use of this technology.  Thereafter, IVF came to be considered as the mainstream medical process for infertile couples to undergo IVF treatment. Thousands of births take place around the world by deploying different IVF and other related techniques that have been developed over the time.

successful birth of Louise Brown

Other Historical Developments in the IVF

Freezing techniques

The development of freezing technique came in the 1980s and it proved to be very helpful for the doctors as they could now limit the number of embryos to be implanted into the uterus to be just one or two to avoid multiple pregnancies and keep them safe for future usage. This technique is extremely useful as it can skip the process of egg retrieval during the future use. There is a significant progress in the imaging techniques that include monitoring using ultrasound to observe the growth and development of eggs prior to retrieval as compared to the laparoscopic surgical method to do the same.

Sperm Retrieval Techniques

Development of TESA (Testicular Epididymal Sperm Aspiration) also brought about a great change by attending to male infertility where selected sperm is injected into the egg to form a healthy embryo.

sperm retrieval techniques

Use of Donor Eggs/ Sperm/ Embryo

For women, who do not produce their own eggs due to various reasons, or men who have poor sperm count or quality concern, use of donor egg and sperm is a boon.  

The ART has since ever been deployed throughout the world to treat different kinds of fertility both in men and women.

Physiologist Robert Edwards won the prestigious Noble Prize in the field of medical science for his contribution in the pioneering work.

First test tube baby came up as an answer to the doubts and questions about the health and normality of the baby as well as the viability of the IVF treatment.

Answers to the questions about test tube baby are available by experts at Elawoman.

IVF, even today is considered as an unethical process by many ethnic groups for different purposes, religion being one of them.  For rest of the others, the IVF and the fertility process is a miracle of God. Now, Louise is almost more than 40 years and she was able to conceive both her sons quite normally. There was no problem or complication giving birth to two children. It’s a blessing for any infertile couple who can choose it at their own convenience.

Points to know: All about the first test tube baby

  • November 1977, IVF experiment was first done
  • Removal of eggs and sperm addition in the laboratory dish to form an embryo took place
  • Embryo implantation was done
  • Louise Brown was born, as the first test tube baby in 1978

So, this was how the birth of Louise Joy Brown brought about a revolution in the field of ART and paved a way for more research and development in the field of infertility treatments.If you wish to know more about IVF treatment and get your own child using the technique, you can check for the best IVF centres at your location.

Dr. Kavita Jaggi Agrawal

About The Author

Infertility Specialist, Obstetrician Dr. Kavita Jaggi Agrawal
Agra

Dr. Kavita Jaggi Agrawal is an obstetrician, gynecologist and infertility specialist who is providing her valuable expertise in the field of gynecology and infertility issues. She ensures that the patients receive the required fertility treatments well on time. Dr. Kavita specializes in the treatments like High Risk Pregnancy Care, In Vitro Fertilization (IVF) and Reproductive Medicine. Currently, she is practicing at Amit Jaggi Memorial Hospital, Vibhav Nagar, Agra.

SOURCES AND REFERENCES:

  1. What is in-vitro fertilization (ivf) and its needs IVF process, Elawoman - 2017
  2. What is ivf (in- vitro fertilization)? IVF, Elawoman - 2018
  3. Male infertility treatment with tesa TESA, Elawoman - 2017
  4. All you need to know about mesa MESA, Elawoman - 2017
  5. Best ways to boost sperm count and increase male fertility Sperm, Elawoman - 2017
  6. When and why women go for the donor eggs Egg, Elawoman - 2017
  7. All you need to know about embryo freezing Embryo freezing, Elawoman - 2017
  8. Blocked fallopian tubes causes and treatment fallopian tube, Elawoman - 2017
  9. Artificial insemination and infertility treatment artificial insemination, Elawoman - 2017
  10. Exercise during pregnancy for normal delivery normal pregnancy, Elawoman - 2018

6 Comments

user_img

Jigyasha Paresh

After the introduction of IVF, various other infertility treatment were introduced like Semen freezing, surrogacy and many more.

Oct. 13, 2018, 11:24 p.m. 5.0

user_img

Ankita Pradhan

I never knew IVF is around half a century old infertility treatment. Many parents are blessed with this practice. Good article!

Oct. 1, 2018, 9:56 a.m. 4.5

user_img

Kavita Tyagi

It was a good read, Many thanks for sharing this!

Sept. 13, 2018, 6:34 a.m. 4.5

user_img

Hari Kishan Gupta

Many thanks to the scientist Robert Edward and doctor Patrick Steptoe for their breakthrough experiment. They helped millions of parents to conceive.

Sept. 12, 2018, 1:11 p.m. 5.0

user_img

Arevena Patel

Such an emotional story. The luckiest parents ever, they must have gone through a lot.

Aug. 25, 2018, 11 a.m. 5.0

user_img

Somendra Priyabroto

Aug. 24, 2018, 7:06 p.m. 4.5

View all comments

Leave a Comment

Rating

Disclaimer

The information displayed on this webpage covers general information on several medical conditions, fertility treatments, IVF ICSI, surrogacy procedure, home remedies, and their respective treatments. The exclusive purpose of the displayed information is for the sake of general understanding and it has been collected from open sources which heavily rely on research and laboratory tests. However, the information shared here should not be considered as a medical advice or an alternative to consultation with a registered medical practitioner or licensed healthcare professional.

It is not advised to self-diagnose or treat any medical condition or disease following the information given in this article. We insist you to consult a registered practitioner and never try to replace their advice or discontinue treatment in between by relying solely on the information obtained. External links to different websites as well as videos given on the website serve the purpose of sharing knowledge only. Ela being an Independent Medical Information platform is neither responsible nor guarantees the authenticity, reliability, and accuracy of these videos and websites in any way. We do not intend the information displayed here to be used for a medical emergency, if you seek medical attention for yourself (or any other person with whom you want to share the information with), we advise you to directly get in touch with the hospital or the doctor.

Related Article view all

Fertility Treatments
Advantages and Disadvantages of ZIFT
Dr. Mukta Kapila
Dr. Mukta Kapila 4.5 (1 Votes)

Advantages and Disadvantages of ZIFT

Termed as the modified version of IVF, Zygote IntraFallopian Transfer (ZIFT) is an Assisted Reproductive Technology (ART) method, used in cases where blocked fallopian tube/s make it impossible for sperm to reach egg for fertilization. Know more about ZIFT process, its cost and advantages.

Read More

Fertility Treatments
Embryo Freezing, Embryo Cryopreservation and Thawing Process
Dr. Neha Gupta
Dr. Neha Gupta 4.5 (1 Votes)

Embryo Freezing, Embryo Cryopreservation and Thawing Process

Embryo freezing is a process that allows an embryo to be frozen for a specific period for future pregnancy. Enhance your understanding on processes of Slow Programmable Freezing and Vitrification along with benefits and disadvantages of embryo freezing.

Read More

Fertility Treatments
What are the Chances for IVF Treatment Success?
Dr. Arti Gupta
Dr. Arti Gupta 4.8 (6 Votes)

What are the Chances for IVF Treatment Success?

A number of factors can impact the result in an IVF cycle. Hence one must be aware of the fact that factors like age, previous pregnancy records, type of infertility problem and life-style etc are very much capable of deciding the fate of the IVF cycle. Success rate for young couples is more than 40% while couples aged more than 35 years have lesser chances of IVF success.

Read More

More From Author

Planning Baby
How Often Should You Have Sex When Trying To Conceive

How Often Should You Have Sex When Trying To Conceive

Wondering how to get pregnant fast. Deliberating whether frequent s...

Read More

Planning Baby
Must know risk factors of Pregnancy after 30

Must know risk factors of Pregnancy after 30

How to become pregnant after your 30. Keep track of ovulation days ...

Read More

Planning Baby
Faint lines on Pregnancy Test

Faint lines on Pregnancy Test

Getting pregnant is on your mind, you have used the ovulation perio...

Read More

Trending Articles

surrogacy
surrogacy

5 Best Surrogacy Doctors in India

Find the list of best surrogacy doctors in India who offers the best treatment with the highest success rate. The list has been categorized on the basis of doctors fame, experience, reviews, ratings, and cost. Dr. Mohit Saraogi from Saraogi Hospitals and IRIS IVF Centre and Dr. Kaberi Banerjee from Advanced Fertility Centre top the list of the best surrogacy doctors in India.

Read More 4.5 (1 Votes)

IVF
ivf

Best IVF Doctors in India with Highest Success Rates

Find here the list of best IVF doctors in India on the basis of Ratings, Success Rate, Services offered, IVF cost packages and available Facilities. Dr. Nisha Bhatnagar, Dr. Kaberi Banerjee and Dr. Anjali A Deval top the list of such IVF doctors in India due to their unique pricing system, popularity and high success rate.

Read More 4.7 (3 Votes)

surrogacy
surrogacy

Top Surrogacy Centres in India with Highest Success Rates

In this article we bring you the best Surrogacy Centers and clinics in India with Review Ratings, Cost Estimates, and Surrogacy Success Rate to help you make the best choice. Aveya IVF and Surrogacy Centre and Advanced Fertility and Surrogacy Centre tops the list of such surrogacy centres in India due to their low treatment costs, popularity and high success rates.

Read More 4.8 (2 Votes)