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17 January 2017

What is ICSI

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Written by Dr. Neha Gupta
ICSI is a infertility treatment for male infertility, which include IVF treatment or IVF procedure. This infertility treatment is used to cure sperm related issues in order to make test tube baby successful

ICSI is a infertility treatment for male infertility, which include IVF treatment or IVF procedure. This infertility treatment is used to cure sperm related issues in order to make test tube baby successful

ICSI is a process in which a single sperm is directly injected into an egg to fertilize it and then the fertilized egg is transferred into the womb and one of the infertility treatment. It is one the best cost-effective and successful treatment. This method is especially for men who have low or zero sperm count or motility. In the case of zero sperm count or when the male partner is uptight to ejaculate on the day of egg collection for IVF procedure or IVF treatment, the sperm is extracted either from testicles (using TESA) or epididymis (using MESA).

A sharp and delicate needle is used to extract a sperm and then it is injected into the egg, after which the needle is removed. The success rate of ICSI is higher than IVF as an infertility treatment. The success rate of ICSI treatment is directly proportional to the age: the younger the patient is; the higher are the chances of success.

Sometimes, due to physiological deficiencies that may lead to the drastic reduction or absence in the production of gametes or due to poor gamete quality or defects in the interaction, the process of fertilization can be diminished.

From the Assisted Reproduction Techniques (ART) perspective there are two main approaches to overcome these deficiencies: Conventional In Vitro Fertilization (IVF) and Intra Cytoplasmic Sperm Injection (ICSI).

ICSI treatment, IVF treatment

Who is IVF-ICSI Treatment Recommended for?

ICSI treatment-IVF treatment is for the couples who have had poor or no fertilization during standard IVF treatment or IVF procedure, as well as men who have:

  1. Poor sperm morphology

  2. Poor sperm motility (slow moving)

  3. A low sperm count

  4. An obstruction such as a vasectomy, which prevents sperm release

  5. Antisperm antibodies

  6. A vasectomy reversal that was unsuccessful or resulted in a low sperm count or poor-quality sperm

Are There Any Specific Situations Where ICSI Might Be Recommended?

ICSI treatment may be recommended only when there is a reason to suspect that achieving fertilization naturally may be difficult.

ICSI treatment is most often used by the couples who are dealing with male infertility. Male infertility factor includes any of the following: Low sperm counts, poor motility or movement of the sperm, poor sperm quality, sperm that lack the ability to penetrate an egg or azoospermia.

Azoospermia is a medical condition where there is no sperm discharge through the male’s ejaculation. There are two types of azoospermia: obstructive and non-obstructive.

Infertility Treatment, IVF

Obstructive azoospermia may be caused by any of the following:

  1. Previous vasectomy

  2. Congenital absence of vas

  3. Scarring from prior infections

Non-obstructive azoospermia occurs when a defective testicle is not producing healthy sperm count. In the case of azoospermia, the probability of obtaining healthy sperm is very low.

Why is ICSI done?

  1. ICSI is used to treat male infertility where little or no sperm is ejaculated in the semen. Immature sperm retrieved from the testicles usually can't move and are more likely to fertilize an egg through ICSI.
  2. ICSI treatment can be used when a couple's infertility is not related to the problem of sperms. Some couples choose to try ICSI treatment after repeat in vitro fertilization that has not worked.
  3. ICSI is also used by the couples who plans to test the embryo for certain genetic problems. ICSI uses only one sperm for each egg.

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