fertility treatments

Zygote Intrafallopian Transfer - Process, Advantages, Disadvantages and Cost

  • 4.7   (6 Votes)
Medically Reviewed by Dr. Deepika Tiwari - MBBS on 03 Jan 2019 - Written by Dr. Mukta Kapila - MBBS - Grammatically Approved by Dr. Kavita Jaggi Agrawal - MBBS

Zygote Intrafallopian Transfer is an ART which is used to stimulate ovulation. The advantages of ZIFT is that the procedure ensures that fertilized eggs are inserted into fallopian tubes. The success rates of ZIFT varies from one patient's case to another and ZIFT cost varies accordingly.

Let’s Discuss in More Details About ZIFT:

Each couple imagines conceiving their baby in the natural and sound way. However, in today’s unhealthy lifestyle, infertility has become a major issue. Wrong eating habits, stressful work schedules, irregular eating habits, and many such unhealthy ways prompt high odds of infertility issues. With continually evolving science and research, ZIFT or Zygote IntraFallopian Transfer is another addition to ART (Assisted Reproductive Technology) that doctors are recommending widely for infertile couples to get a baby.

Why opt for ZIFT?

ZIFT is a choice for couples if they have tried different medicines and all have proved to be unsuccessful in leading to pregnancy. For this process, there should be at least one open fallopian tube. ZIFT can likewise help considering you have the following conditions:

  • Unexplained infertility
  • Ovulation issues
  • Your accomplice has a low sperm check

If the sperm-check is low in the male partner, or if there were preparation issues in past IVF cycles, ZIFT can be utilized in combination with Intracytoplasmic Sperm Injection (ICSI). ICSI is a strategy that lifts the shot of treatment by infusing a solitary sperm specifically into an egg.

The process of ZIFT as Compared to IVF

ZIFT is a modified version of In Vitro Fertilization (IVF). ZIFT process takes place four to six weeks to complete one treatment cycle. This treatment is performed when a blockage in the fallopian tube prevents the normal binding of sperm to the egg.

  • In this process, first, ovaries are stimulated with the help of medicines. This is done to increase the chances of producing multiple eggs.
  • After that, the produced eggs are collected through an aspiration procedure.
  • These collected eggs are fertilized in a laboratory. Now the fertilized eggs are transferred, versus 3-5 days as used in a regular IVF cycle.
  • The fertilized eggs are then transferred to fallopian tube within 24 hours through a laparoscopic procedure. It is done through a catheter placed deep in the fallopian tube.
  • In the final step is to notice the early pregnancy symptoms. The doctor will use blood to confirm if pregnancy has occurred.

Advantages and Disadvantages of ZIFT Process

There are always pros and cons both associated with anything. If there are advantages of ZIFT then there are also some risks of this procedure. Therefore, here we are giving a brief of the pros and cons of ZIFT.

Advantages of ZIFT:

  • Those couples who have extreme infertility issues can think about this strategy as help to have their baby.
  • The best thing about this technique is that the specialist can affirm the treatment of egg before inserting it in the Fallopian tube.
  • In this way, the specialist will just choose the best and splendidly created zygote.
  • This strategy functions admirably on those couples who have attempted no less than one year to conceive normally and have 5 to 6 fizzled cycles of IUI (Intrauterine Insemination).

Disadvantages of ZIFT:

There are certain disadvantages or risks associated with this strategy and accordingly not all couples settle on ART or, to be precise, ZIFT.

  • In this technique, different zygotes are embedded in the fallopian tube to build the odds of accomplishment, yet it can likewise come about into multiple pregnancies. Along these lines, the chances of having twins and triplets increases. Occasionally, different pregnancies can be hazardous and there are more odds of an unnatural birth cycle. 
  • There is a danger of having an ectopic pregnancy, where the hatchling will create outside the womb in the fallopian tube itself. In such cases, it becomes necessary to expel the zygote through surgery or even the fallopian tube as well. 
  • A few women may grow excessively numerous eggs because of the fruitfulness of drugs. This can cause a few hormonal changes in the body, which are hard to deal with. 
  • A few examinations additionally guarantee that infants conceived through this treatment can have birth imperfections or disorders.

Effectiveness of ZIFT

The achievement rate for ZIFT differs drastically. It highly depends on a couple's fertility issue and age. Women that are more youthful have more advantageous eggs and higher achievement rates. Ladies have around a twenty-two percent possibility of conveying an infant with each ZIFT cycle.

Similarities and Dissimilarities Between ZIFT and IVF

  • ZIFT and IVF both have a tendency to be ideal medications for women who have more serious infertility issues, for example, harmed fallopian tubes. 
  • ZIFT and IVF both include incipient organism culture. 
  • ZIFT and IVF both furnish the doctor with the chance to choose the best quality embryo for transfer.
  • ZIFT transfers the treated fertilized egg is put into the fallopian tube while in IVF; the prepared embryo is transferred into the uterus.
  • The ZIFT system varies from IVF in a way that it requires an additional surgical method called laparoscopy to transfer the embryo in the fallopian tube.

Why is ZIFT a Better Choice?

  • ZIFT (Zygote Intrafallopian transfer) is a superior choice of other infertility treatment methods. Here the developed Zygote is transferred in the fallopian tube and not in a petri dish or uterus. The pregnancy rates with ZIFT have dependably been higher than with In Vitro Fertilization-Embryo Transfer (IVF-ET) and there are numerous purposes behind this. 
  • The fallopian tube gives a superior domain to the embryo when contrasted with an incubator.
  • There is better synchronization between the embryo and uterus in a ZIFT, because of which implantation rates are superior as compared with customary IVF treatment.
  • ZIFT enables the specialist to sidestep the cervix. This can be exceptionally useful in women with cervical stenosis, or the individuals who have experienced failed IVF treatment in the past. It is so because the embryo exchange is actually troublesome or inappropriate.

Cost of ZIFT Procedure

ZIFT is an expensive procedure. It typically costs from $15,000 to $ 20,000 a cycle. The cost depends upon your location, the number of medicines taken, and the number of cycles you undergo. ZIFT may cost more than traditional In Vitro Fertilization. Before going for such treatments, make sure that you are with the best specialist because ultimately the success of the treatment is all that matters. Also, be prepared that your budget allows you to go for this treatment.

Make sure you set aside the opportunity to completely examine the consequences of fertility tests and the diverse medicines for infertility with your specialist before settling on any choices about what will be best for you. This will help in making the correct decisions and increasing the chances of effective conceiving.

I hope the article helped you with getting all the information related to Zygote Intrafallopian Transfer (ZIFT) along with the pros and cons of the same. Follow Elawoman blog to get all the latest updates regarding infertility treatments, IVF, IUI, and Surrogacy. You can also call on the given number for any ART-related query or to book an appointment- +917899912611.

Dr. Mukta Kapila

Written by

Laparoscopic Surgeon, Gynecologic Surgeon

Dr. Mukta Kapila is counted among the highly-regarded laparoscopy surgeon and obstetrician in Gurgaon. She acquired MBBS from Govt. Medical College in Amritsar in 1986, followed by DGO from Armed Forces Medical College in 1991 and DNB from MNAMS Pune University in 1998. She is a renowned gynecologist and obstetrician with a great experience of more than two decades. She is a member of the Association of Obstetrics and Gynaecologists of Delhi, Federation of Obstetrics and Gynaecological Societies of India and Indian Association of Gynaecological Endoscopists. She specializes in Caesarean Section, Hysterectomy, High-Risk Pregnancy Care, Normal Vaginal Delivery and Laparoscopic Surgery. Dr. Mukta Kapila has an expertise in Intrauterine Insemination and is practicing at Fortis Memorial Research Institute in Gurgaon and Dr. Mukta Kapila Clinic. You can reach out for her contact details at elawoman.com



Aisha Khan

My husband has a low sperm check, so on our doctor's suggestion, we went for ZIFT with ICSI. The treatment went to be successful.

Nov. 26, 2018, 2:37 p.m. 4.5


Rajnish Dutta

I think ZIFT is a very expensive treatment as compared with other infertility treatments. Only couples who don't have any budget issues can easily go for ZIFT, otherwise, you should think twice before proceeding further.

Nov. 21, 2018, 4:11 p.m. 5.0


Mr. and Mrs. Ramakant

After studying our situation and seeing our past failures doctor was in favor of ZIFT for us. It was a successful treatment in our case.

Nov. 15, 2018, 11:40 a.m. 4.5


Niharika Dave

I had experienced many past infertility treatment failures. Now I am going for ZIFT. Hope it will be a successful treatment.

Nov. 3, 2018, 6:45 p.m. 4.5


Siddhant Kala

ZIFT is a better option for those who have blocked fallopian tube or some unexplained infertility.

Nov. 2, 2018, 9:03 a.m. 5.0


Sragvibhushan Radia

Our 3 cycles of IVF have failed already. I think ZIFT is a way ahead for us.

Oct. 31, 2018, 5:59 p.m. 4.5

View all comments

Leave a Comment



The information displayed on this webpage covers general information on several medical conditions, fertility treatments, IVF ICSI, surrogacy procedure, home remedies, and their respective treatments. The exclusive purpose of the displayed information is for the sake of general understanding and it has been collected from open sources which heavily rely on research and laboratory tests. However, the information shared here should not be considered as a medical advice or an alternative to consultation with a registered medical practitioner or licensed healthcare professional.

It is not advised to self-diagnose or treat any medical condition or disease following the information given in this article. We insist you to consult a registered practitioner and never try to replace their advice or discontinue treatment in between by relying solely on the information obtained. External links to different websites as well as videos given on the website serve the purpose of sharing knowledge only. Ela being an Independent Medical Information platform is neither responsible nor guarantees the authenticity, reliability, and accuracy of these videos and websites in any way. We do not intend the information displayed here to be used for a medical emergency, if you seek medical attention for yourself (or any other person with whom you want to share the information with), we advise you to directly get in touch with the hospital or the doctor.

More From Author

Block Schedules - Know all the Advantages of Block Scheduling for Students and Teachers

Block Schedules - Know all the Advantages of Block Scheduling for Students and Teachers

posted on 31 Oct 2018 4.7/ 5

Block Schedules is an academic class routine which are followed in schools. There are various block scheduling advantages for students as well as for teachers. Some mo...

Read More

Love and Relationships
25 Best Depression Quotes on Life and Love that motivate in Life

25 Best Depression Quotes on Life and Love that motivate in Life

posted on 31 Oct 2018 4.7/ 5

Feeling depression can be tremendously isolating. One person can read all time inspirational and motivating quotes on life to self-motivate from time to time. Reading ...

Read More

In Vitro Fertilisation (IVF)
IVF Treatment - Procedure, When is it Required, Cost and Success Rate

IVF Treatment - Procedure, When is it Required, Cost and Success Rate

posted on 31 Oct 2018 4.7/ 5

IVF treatment is an assisted reproductive technology which assists in conceiving a baby. IVF is required for women who are above 40 years blocked fallopian tubes, ovul...

Read More

Related Article view all

Fertility Treatments
Male infertility - Causes of Infertility, Male infertility tests

Most of the men with male infertility issues think about how to increase sperm count. Male infertility causes include chemotherapy, genetic abnormalities, undescended testicle, and infections of testicles. Male infertility tests includes Sperm Analysis test, Testicular Biopsy, and Hormone Evaluation.

Read More

Fertility Treatments
Effect of infertility drugs on Premature Menopause - When to worry, What to do

Premature menopause concerns most of the woman who are still away from the phase of menopause. Infertility drugs especially ovulation induction drugs can impact the periods in your 40's. So, it is important to consult your infertility specialist before you reach any self conclusion.

Read More

Fertility Treatments
Most In Demand Infertility Treatments for Couples with high success rates

Infertility treatments such as IVF treatment, ICSI treatment along with use of other assisted reproductive technology prove to be useful for couples who are trying to conceive. Surgical procedures are performed for PCOS treatment, Fallopian tube blockage treatment, fibroids, and endometriosis.

Read More

Trending Articles


5 Best Surrogacy Doctors in India

posted on 31 Oct 2018 4.5 / 5(1 Votes)

Find the list of best surrogacy doctors in India who offers the best treatment with the highest success rate. The list has been categorized on the basis of doctors fame, experience, reviews, ratings, and cost. Dr. Mohit Saraogi from Saraogi Hospitals and IRIS IVF Centre and Dr. Kaberi Banerjee from Advanced Fertility Centre top the list of the best surrogacy doctors in India.

Read More


Best IVF Doctors in India with Highest Success Rates

posted on 31 Oct 2018 4.7 / 5(3 Votes)

Find here the list of best IVF doctors in India on the basis of Ratings, Success Rate, Services offered, IVF cost packages and available Facilities. Dr. Nisha Bhatnagar, Dr. Kaberi Banerjee and Dr. Anjali A Deval top the list of such IVF doctors in India due to their unique pricing system, popularity and high success rate.

Read More


Top Surrogacy Centres in India with Highest Success Rates

posted on 31 Oct 2018 4.8 / 5(2 Votes)

In this article we bring you the best Surrogacy Centres and clinics in India with Review Ratings, Cost Estimates, and Surrogacy Success Rate to help you make the best choice. Aveya IVF and Surrogacy Centre and Advanced Fertility and Surrogacy Centre tops the list of such surrogacy centres in India due to their low treatment costs, popularity and high success rates.

Read More