Ovulation, Period, Pregnancy and IVF
Home Blog Fertility Basics About Unexplained Infertility And Its Treatment
15 January 2017

About Unexplained Infertility And Its Treatment

Written by Dr Sunil Eshwar
Female and male infertility issues are common these days and can be treated with fertility treatments. Unexplained fertility can affect your chances of conceiving

Female and male infertility issues are common these days and can be treated with fertility treatments. Unexplained fertility can affect your chances of conceiving

Unexplained infertility is a very common term we hear in the reproductive world. Unexplained infertility is the term used when there is no proven or found cause for infertility in men and women.Commonly happens that the couple go through all of the infertility tests available and everything comes back clear. This is of corse a good news but can be so frustrating at times when you have not got pregnant after so many years of TTC. In such cases of unexplained infertility, it is too hard to figure out what to do next.

Sometimes it could be as simple as some kind of nutritional deficiency, the inaccurate timing of sexual intercourse, a pre-existing health issue, or it may be that you need to explore options. It is important to cover all the basics, including additional testing that may need to take place. We are now going to cover the important areas that need to be focussed, some areas may or may not apply to you, but some may not have been taken into consideration when you were given your diagnosis.

What Role Hormonal Balance Play?

If the hormones are not balanced or there is some issues with the menstrual cycle is, it's hard to believe that you cannot get pregnant. Even if pregnancy does occur, the risk of miscarriage may increase. This is important for the male partner to know as well. Men can also have a hormonal imbalance as well, which may also create issues and difficulties in becoming pregnant due to poor sperm health or motility or sperm count, or other health-related issues.

What problems may women have?

Menstrual cycle irregularities or painful menses or excessive bleeding may be a sign of hormonal imbalance in women or other more severe fertility issues. If any of the below hormones are not at the correct levels, the menstrual cycle may become irregular or you may face excessive bleeding or cramping. Hormonal imbalance may cause lots of other health related issues. For example thinning hair, heart palpitations, low libido, depression, over stress etc.

  1. Progesterone
  2. Estrogen
  3. Follicle Stimulating Hormone (FSH)
  4. Luteinizing Hormone (LH)
  5. Androgens, for example, DHEA, Testosterone
  6. Thyroid hormones
  7. Prolactin

How Can Cervical Mucous Be A Problem?

Low cervical mucous is one of the most important factors to becoming pregnant. If the cervical mucous is nonexistent or too acidic, scant, then the sperm will not be able to make their way to the cervix.

What Are The Other Health Related Factors and Problems that Affect Both Women and Men’s Fertility?

Hormonal imbalance, poor egg health, low ovarian reserve, or poor/abnormal immune response which may affect conception badly. If you have any of the below health issues, it is very important to first watch out those issues, because problems with any of the below may directly impact your ability to conceive.

  1. Thyroid issues
  2. Poor Adrenal Health
  3. Very low body weight
  4. Obesity
  5. Diabetes
  6. Autoimmune disease
  7. Smoking

Stress: Our bodies sometimes prevent the conception during the times of extreme stress. The presence of adrenaline and the hormone that is released by our bodies during some stressful times signals to our body that such conditions are not ideal for conception. It also makes the pituitary gland to release higher levels of prolactin, this also contributes to infertility that prevents conception from curing. High stress levels can impact fertility for both female and male and need to opt for some fertility treatment.

What Are The Necessary Testing for diagnoses a couple with unexplained infertility?

There is a wide range of infertility tests that doctors do before they diagnose a couple with such unexplained infertility issues. Be sure you get the following hormones tested.

Full hormone panel including:

  1. Progesterone
  2. Estradiol
  3. Follicle Stimulating Hormone (FSH)
  4. Luteinizing Hormone (LH)
  5. Androgens (ex: testosterone/DHEA)
  6. Thyroid hormone levels
  7. Prolactin levels
  8. Homocysteine levels
  9. Immunological markers

What Is Immunological Fertility Testing?

A Reproductive Immunologist always differs from a Reproductive Endocrinologist, which most couples are referred, when infertility issues are not found by an OB-GYN.

  1. Two or more than 2 miscarriages after the age of 35
  2. Two IVF cycle failures after the age of 35
  3. 3 or more miscarriages before the age of 35
  4. 1 or more failed IVF before the age of 35
  5. Pre-existing immune problems (Lupus, Rheumatoid Arthritis, MS)
  6. Unexplained Infertility diagnosis
  7. Previous pregnancies showing retarded and bad fetal growth
  8. Endometriosis and at stage 1 & 2
  9. Cold and flu-like symptoms, sore throat noted regularly after ovulation, IUI, or IVF transfer

What Are The Natural Options for Unexplained Infertility?

If you have been diagnosed with infertility for unknown reasons or unexplained fertility, what should you do then? Let’s start by taking a good look at daily lifestyle and eating habits and then what you can do naturally to conceive? You may need to opt for the fertility treatment.

The great thing about herbs and natural therapies or organic products is that the focus is on bringing the body back into balance to live a healthy life. With unexplained infertility, there are a few areas you can look into.

Eat a Fertility Diet: Diet and some foods are the most important way to support fertility health and even boost the fertility and avoid you going for the fertility treatment. Having a nutritional deficiency can cause the menstrual cycle to become imbalanced with irregular periods, may cause a lack of beneficial hormones to be produced, this may also contribute to poor sperm count and health or cause the body to lack overall health.

Eat Whole Foods: Fresh vegetables, fruits, raw seeds and nuts, whole grains, lean grass fed free range organic meats and dairy products. 

You May Also Like

Fertility Basics

What is ovulation and how do you check ovulation period and ovulation Symptoms are some of the questions we always find it hard to understand when we plan or avoid pregnancy
Read More

Dr. Sailaja Vuppu
Fertility Basics

What is ovulation and how do you check ovulation period and signs of ovulation are some of the questions we always strive to understand when we plan or avoid pregnancy. Here is our guide for all your queries on ovulation, ovulation period or ovulation cycle and ovulation symptoms.
Read More

Dr. Chitwan Dubey
Fertility Basics

Discover and explore the meaning, signs, reasons, myths, natural home remedies and treatments to Nightfall problems.
Read More

Dr. Sohani Verma

More From Author

Fertility Basics

Infertility is a concerning problem.You should keep a track on ovul...
Read More

Dr Sunil Eshwar
Fertility Basics

Infertility Profiling Tests help you pin down the reason behind you...
Read More

Dr Sunil Eshwar
Fertility Basics

About one third of infertility cases in the world are due to women ...
Read More

Dr Sunil Eshwar


Ankit Sharma
April 5, 2017, 11:08 a.m.
Good article