Top Indian Cities
  • Delhi
  • Kolkata
  • Mumbai
  • Bangalore
  • Hyderabad
  • Lucknow
  • Pune
  • Ahmedabad
  • Chennai
  • Patna
  • Jaipur
  • Indore
  • Gurgaon
  • Surat
  • Bhopal
  • Nagpur
  • Varanasi
  • Noida
  • Kanpur
  • Ranchi
  • Amritsar
  • Udaipur
  • Ludhiana
  • Srinagar
  • Agra
  • Chandigarh
  • Allahabad
  • Bhubaneswar
  • Vadodara
  • Guwahati
  • Rajkot
  • Ghaziabad
  • Faridabad
    Top Global Cities
  • Abu Dhabi
  • Bangkok
  • Cebu City
  • Chiang Mai
  • Chittagong
  • Colombo
  • Depok
  • Dhaka
  • Doha
  • Dubai
  • Eldoret
  • Ipoh
  • Jakarta
  • Johor Bahru
  • Kathmandu
  • Khon Kaen
  • Kiev
  • Klang
  • Kota Damansara
  • Kuala Lumpur
  • London
  • Makati
  • Malacca
  • Manila
  • Minsk
  • Monroe
  • Nairobi
  • Odessa
  • Padang
  • Penang
  • Phnom Penh
  • Phuket
  • Quezon City
  • Selangor
  • Singapore
  • Tbilisi
    pink loader
    fertility basics

    Unexplained Infertility - Various Aspects of Unexplained Infertility

    • 4.8   (5 Votes)
    Medically Reviewed by Dr. Deepika Tiwari - MS, MBBS on 16 Jul 2018 - Written by Dr. Sunil Eshwar - MD, MBBS, DNB - Grammatically Approved by Dr. Kavita Jaggi Agrawal - MS, MBBS

    Unexplained infertility is one of the types of infertility which is usually underestimated among male and female infertility issues. Immunological fertility tests are useful in determining the cause of infertility with efficient results. Consumption of fertility diet and whole foods prove to be useful for men and women.

    Unexplained infertility is a very common term we hear in the reproductive world. Unexplained infertility is the term used when there is no proven or found cause for infertility in men and women. Commonly happens that the couple goes through all of the infertility tests available and everything comes back clear. This is of course a good news but can be so frustrating at times when you have not got pregnant after so many years of TTC. In such cases of unexplained infertility, it is too hard to figure out what to do next.

    Sometimes it could be as simple as some kind of nutritional deficiency, the inaccurate timing of sexual intercourse, a pre-existing health issue, or it may be that you need to explore options. It is important to cover all the basics, including additional testing that may need to take place. We are now going to cover the important areas that need to be focussed, some areas may or may not apply to you, but some may not have been taken into consideration when you were given your diagnosis.

    What Role Hormonal Balance Play?

    If the hormones are not balanced or there is some issues with the menstrual cycle is, it's hard to believe that you cannot get pregnant. Even if pregnancy does occur, the risk of miscarriage may increase. This is important for the male partner to know as well. Men can also have a hormonal imbalance as well, which may also create issues and difficulties in becoming pregnant due to poor sperm health or motility or sperm count, or other health-related issues.

    What problems may women have?

    Menstrual cycle irregularities or painful menses or excessive bleeding may be a sign of hormonal imbalance in women or other more severe fertility issues.

    Unexpalined Infertility, Fertility Treatment

    If any of the below hormones are not at the correct levels, the menstrual cycle may become irregular or you may face excessive bleeding or cramping. Hormonal imbalance may cause lots of other health related issues. For example thinning hair, heart palpitations, low libido, depression, overstress etc.

    • Progesterone
    • Estrogen
    • Follicle Stimulating Hormone (FSH)
    • Luteinizing Hormone (LH)
    • Androgens, for example, DHEA, Testosterone
    • Thyroid hormones
    • Prolactin

    How Can Cervical Mucous Be A Problem?

    Low cervical mucus is one of the most important factors to becoming pregnant. If the cervical mucus is nonexistent or too acidic, scant, then the sperm will not be able to make their way to the cervix.

    What Are The Other Health Related Factors and Problems that Affect Both Women and Men’s Fertility?

    Hormonal imbalance, poor egg health, low ovarian reserve, or poor/abnormal immune response which may affect conception badly. If you have any of the below health issues, it is very important to first watch out those issues, because problems with any of the below may directly impact your ability to conceive.

    • Thyroid issues
    • Poor Adrenal Health
    • Very low body weight
    • Obesity
    • Diabetes
    • Autoimmune disease
    • Smoking

    Stress: Our bodies sometimes prevent the conception during the times of extreme stress. The presence of adrenaline and the hormone that is released by our bodies during some stressful times signals to our body that such conditions are not ideal for conception. It also makes the pituitary gland to release higher levels of prolactin, this also contributes to infertility that prevents conception from curing.

    Male Infertility, Infertility

    High stress levels can impact fertility for both female and male and need to opt for some fertility treatment.

    What Are The Necessary Testing fordiagnosesa couple with unexplained infertility?

    There is a wide range of infertility tests that doctors do before they diagnose a couple with such unexplained infertility issues. Be sure you get the following hormones tested.

    Full hormone panel including:

    • Progesterone
    • Estradiol
    • Follicle Stimulating Hormone (FSH)
    • Luteinizing Hormone (LH)
    • Androgens (ex: testosterone/DHEA)
    • Thyroid hormone levels
    • Prolactin levels
    • Homocysteine levels
    • Immunological markers

    What Is Immunological Fertility Testing?

    A Reproductive Immunologist always differs from a Reproductive Endocrinologist, which most couples are referred, when infertility issues are not found by an OB-GYN.

    • Two or more than 2 miscarriages after the age of 35
    • Two IVF cycle failures after the age of 35
    • 3 or more miscarriages before the age of 35
    • 1 or more failed IVF before the age of 35
    • Pre-existing immune problems (Lupus, Rheumatoid Arthritis, MS)
    • Unexplained Infertility diagnosis
    • Previous pregnancies showing retarded and bad fetal growth
    • Endometriosis and at stage 1 & 2
    • Cold and flu-like symptoms, sore throat noted regularly after ovulation, IUI, or IVF transfer

    What Are The Natural Options for Unexplained Infertility?

    If you have been diagnosed with infertility for unknown reasons or unexplained fertility, what should you do then? Let’s start by taking a good look at daily lifestyle and eating habits and then what you can do naturally to conceive? You may need to opt for the fertility treatment.

    Male Infertility, Fertility, Unexplained Infertility

    The great thing about herbs and natural therapies or organic products is that the focus is on bringing the body back into balance to live a healthy life. With unexplained infertility, there are a few areas you can look into.

    Eat a Fertility Diet: Diet and some foods are the most important way to support fertility health and even boost the fertility and avoid you going for the fertility treatment. Having a nutritional deficiency can cause the menstrual cycle to become imbalanced with irregular periods, may cause a lack of beneficial hormones to be produced, this may also contribute to poor sperm count and health or cause the body to lack overall health.

    Eat Whole Foods: Fresh vegetables, fruits, raw seeds and nuts, whole grains, lean grass fed free range organic meats and dairy products. 

    Dr. Sunil Eshwar

    Written by

    Infertility Specialist, IVF Specialist

    Dr. Sunil Eshwar is an Infertility specialist who is presently specializing in laparoscopic surgery, high-risk pregnancies and infertility treatments such as IVF and IUI. Dr. Sunil Eshwar completed his MBBS from Bangalore Medical College and Research Institute in 2000 and MD from Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) in 2004. Later, he completed DNB from National Board of Examination in 2006. Dr. Sunil Eshwar is currently practicing at Apollo Fertility, Brookfield, Bangalore. For more information about Dr. Sunil Eshwar, visit


    • Infertility profiling medical tests - check for causes of infertility  infertility, Elawoman - 2017
    • How to find out the most fertile days to plan pregnancy?  fertility, Elawoman - 2017
    • Top 5 aspects you need to know about infertility treatments to achieve success  fertility treatment, Elawoman - 2017
    • What are the top 5 reasons for delayed periods or irregular periods?  irregular periods, Elawoman - 2017



    Pratima Bishnu

    My progesterone and estrogen level were variable since I took out my birth control patch after using it for one year. It took 6-7 months to normalize and then I was able to conceive.

    June 30, 2018, 9:34 a.m. 4.5


    Ashista Roy

    I have a thyroid issue but I never had a problem like infertility. I think it's because of the healthy diet I have regularly.

    Jan. 2, 2018, 11:02 a.m. 5.0


    Varsha Gautam

    Sexually transmitted diseases or STDs i.e. chlamydia or gonorrhea can cause irritation and perpetual scarring of the fallopian tubes. This can create obstacle in conceiving and can even cause infertility issues for a longer period of time in women.

    Nov. 2, 2017, 2:29 p.m. 5.0


    Shakti Priya

    I have read some facts regarding infertility. It's been found that In Europe, North America and in other parts of the world, 85% of the couples (approx) will conceive within one year if they have regular unprotected sex. The rest 15% have some kind of health issues or it's their lifestyle that hind…

    Nov. 2, 2017, 2:24 p.m. 4.5


    Nitya Rathore

    My son has diabetes at very younger age, will he have trouble like infertility in future? What can I do other than feeding him healthy food?

    May 16, 2017, 9:57 a.m. 5.0

    View all comments

    Leave a Comment



    The information displayed on this webpage covers general information on several medical conditions, fertility treatments, IVF ICSI, surrogacy procedure, home remedies, and their respective treatments. The exclusive purpose of the displayed information is for the sake of general understanding and it has been collected from open sources which heavily rely on research and laboratory tests. However, the information shared here should not be considered as a medical advice or an alternative to consultation with a registered medical practitioner or licensed healthcare professional.

    It is not advised to self-diagnose or treat any medical condition or disease following the information given in this article. We insist you to consult a registered practitioner and never try to replace their advice or discontinue treatment in between by relying solely on the information obtained. External links to different websites as well as videos given on the website serve the purpose of sharing knowledge only. Ela being an Independent Medical Information platform is neither responsible nor guarantees the authenticity, reliability, and accuracy of these videos and websites in any way. We do not intend the information displayed here to be used for a medical emergency, if you seek medical attention for yourself (or any other person with whom you want to share the information with), we advise you to directly get in touch with the hospital or the doctor.

    More From Author

    Fertility Basics
    Fertility infertility - Signs, Causes, Natural remedies of Fertility Disorders

    Fertility infertility - Signs, Causes, Natural remedies of Fertility Disorders

    posted on 12 Dec 2018 4.8/ 5

    Female infertility is on the rise in the recent times. Some of the female infertility causes include blocked or damaged fallopian tubes, ovulation disorders, pelvic adhe…

    Read More

    Fertility Basics
    Infertility profiling medical tests - Check for causes of infertility

    Infertility profiling medical tests - Check for causes of infertility

    posted on 11 Jul 2018 4.8/ 5

    Infertility profiling medical tests include ESR blood test, Thyroid Function Test, AMH test, Complete Blood Count Test, Prolactin, and LH test. Infertility profiling te…

    Read More

    Fertility Basics
    How is female fertility affected with environmental and occupational factors

    How is female fertility affected with environmental and occupational factors

    posted on 11 Jul 2018 4.8/ 5

    Female fertility is affected with occupational and environmental factors. This includes Lead, Ethylene Oxide, Dibromochloropropane, and Chemotherapy side effects. Medica…

    Read More

    Related Article view all

    Fertility Basics
    Know about Human Reproduction with Fertility - Phases of Natural Human Reproduction

    Human reproduction is mainly divided into 3 phases such as Ovulation, Fertilization, and Implantation. Symptoms of ovulation are crucial as they signify fertile period in a woman. Signs of implantation specify that there is a positive pregnancy. You need to consult your fertility doctor to make sure that you take proper care during your pregnancy.

    Read More

    Fertility Basics
    Infertility profiling medical tests - Check for causes of infertility

    Infertility profiling medical tests include ESR blood test, Thyroid Function Test, AMH test, Complete Blood Count Test, Prolactin, and LH test. Infertility profiling tests help in finding out causes of infertility and respective infertility treatment.

    Read More

    Fertility Basics
    Male infertility - Diagnostic tests to detect male infertility

    Diagnostic tests to detect male infertility includes CBC test, ESR test, Blood Sugar test, VDRL test, and Hepatitis test. These medical tests are essential to perform semen analysis, sperm morphology, semen quality, and sperm count. Diagnostic tests offer results based on which male infertility treatments are performed.

    Read More

    Trending Articles


    5 Best Surrogacy Doctors in India

    posted on 27 Dec 2018 4.5 / 5(1 Votes)

    Find the list of best surrogacy doctors in India who offers the best treatment with the highest success rate. The list has been categorized on the basis of doctors fame, experience, reviews, ratings, and cost. Dr. Mohit Saraogi from Saraogi Hospitals and IRIS IVF Centre and Dr. Kaberi Banerjee from Advanced Fertility Centre top the list of the best surrogacy doctors in India.

    Read More


    Best IVF Doctors in India with Highest Success Rates

    posted on 19 Dec 2018 4.7 / 5(3 Votes)

    Find here the list of best IVF doctors in India on the basis of Ratings, Success Rate, Services offered, IVF cost packages and available Facilities. Dr. Nisha Bhatnagar, Dr. Kaberi Banerjee and Dr. Anjali A Deval top the list of such IVF doctors in India due to their unique pricing system, popularity and high success rate.

    Read More


    Top Surrogacy Centres in India with Highest Success Rates

    posted on 20 Dec 2018 4.8 / 5(2 Votes)

    In this article we bring you the best Surrogacy Centres and clinics in India with Review Ratings, Cost Estimates, and Surrogacy Success Rate to help you make the best choice. Aveya IVF and Surrogacy Centre and Advanced Fertility and Surrogacy Centre tops the list of such surrogacy centres in India due to their low treatment costs, popularity and high success rates.

    Read More